BACKGROUND
Maintaining folate stability during sample handling is important, yet challenging.
OBJECTIVE
We investigated the effects of suboptimal preanalytical conditions on serum folate stability.
METHODS
By using an HPLC-tandem MS method we measured folates [5-methyltetrahydrofolate (5-methylTHF), folic acid, MeFox (5-methylTHF oxidation product, pyrazino-s-triazine derivative of 4α-hydro...