Innate immunity has received impressive attention in the past decade owing to the discovery of the Toll like receptors (TLRs) and the NOD-like receptors (NLRs). While the TLRs specialize in fighting microbes at the cell surface, the NLRs complement by detecting and responding to intracellular microbes. Recently, the non-microbe sensing NLR called inflammasomes. have been identified. which sense...

Class I alpha1,2-mannosidases (glycosylhydrolase family 47) are key enzymes in the maturation of N-glycans. This protein family includes two distinct enzymatically active subgroups. Subgroup 1 includes the yeast and human endoplasmic reticulum (ER) alpha1,2-mannosidases that primarily trim Man(9)GlcNAc(2) to Man(8)GlcNAc(2) isomer B whereas subgroup 2 includes mammalian Golgi alpha1,2-mannosida...

the rapid development of internet and electronic businesses have stimulated the banking sector towards encouraging customers to internet banking (ib), however, the evidence indicates a lack of interest in the use of ib services. therefore, this paper aims to identify affecting factors on customer adoption from ib and measure the influence of each factor on ib adoption. based on an explorative l...

objective: comparing the effect of repeated opening of the container lid of two dentin adhesive systems, prime&bond; nt (p&b; nt) and ibond (ib), on shear bond strength. materials and methods: intact bovine lower incisors (n=60), fixed in acrylic were ran-domly divided into six groups (n=10). groups i and ii were set as control groups. p&b; nt and ib were applied on the samples after five days ...

Cucumber mosaic virus (CMV) has a worldwide distribution and the widest host range of any known plant virus. From 2000 to 2012, epidemics of CMV severely affected the production of snap bean (Phaseulos vulgaris L.) in the Midwest and Northeastern United States. Virus diversity leading to emergence of new strains is often considered a significant factor in virus epidemics. In addition to epidemi...

background and objectives:gamma-irradiation is used vastly for both decontamination and sterilization of natural products; but these high-energy rays can affect heat-sensitive essential oils. methods: the oleo-gum-resin of boswellia carterii (burseraceae) was sterilized by γ-irradiation at dose 30 kgy. the essential oils obtained by hydrodistillation of non-irradiated boswellia (nib) and irradi...

Clostridium perfringens iota-toxin is a binary toxin composed of an enzyme component (Ia) and a binding component (Ib). Each component alone lacks toxic activity, but together they produce cytotoxic effects. We examined the cytotoxicity of iota-toxin Ib in eight cell lines. A431 and A549 cells were susceptible to Ib, but MDCK, Vero, CHO, Caco-2, HT-29, and DLD-1 cells were not. Ib bound and for...

Background: Asthma is recognized as a common cause of disability, of great economic cost, and of preventable deaths. In this study we aimed to test our hypothesis to evaluate the relationship between the Human Platelet Antigen-1(HPA-1) polymorphism and bronchial asthma and its severity, which would suggest genetic variances that may be responsible for expression or activation of these receptors...

Inattentional Blindness (IB) occurs when an observer who is engaged in a resource consuming task fails to notice an unexpected although salient stimulus appearing in his/her visual field. The incidence of IB can be affected by changes in stimulus-driven properties of the display, but very little research has examined individual differences in propensity for IB. The current research examines ind...

The Col Ib-P9 plasmid content of colicinogenic cells has been measured by both sedimentation analysis of cleared lysates and by deoxyribonucleic acid hybridization to purified Col Ib-P9 factor deoxyribonucleic acid. The results show an independence between mitomycin C-induced colicin synthesis and Col Ib-P9 replication. In addition, the ratio of the various molecular configurations (i.e., coval...