Subcutaneous panniculitis-like T-cell lymphoma is a distinct variant of cutaneous T-cell lymphoma, characterized by primary involvement of the subcutaneous fat in a manner mimicking panniculitis. It accounts for less than one percent of all non Hodgkin lymphoma. We describe two such patients who presented with cutaneous nodules. A 28 year old male presented with a one and a half month history o...

OBJECTIVE One-third of men with type 2 diabetes have hypogonadotropic hypogonadism (HH). We conducted a randomized placebo-controlled trial to evaluate the effect of testosterone replacement on insulin resistance in men with type 2 diabetes and HH. RESEARCH DESIGN AND METHODS A total of 94 men with type 2 diabetes were recruited into the study; 50 men were eugonadal, while 44 men had HH. Insu...

cancer cell-stromal cell interaction plays a crucial role in the growth and invasion of tumor cells of various organs. it has been recently suggested that adipocytes and preadipocytes, two specific types of stromal cells, affect the biological behavior of variety of breast cancer cell lines. in spite of few investigations, there is a controversy in the literatures about the effects of adipocyte...

Figure 1. Intraoperative photograph demonstrating disruption of anterior table of frontal bone following debulking of subcutaneous mass.

Subcutaneous tissue is a rare site of metastasis, accounting for only 1–2% of all lung neoplasms. Positron emission tomography (PET) using F-fluorodeoxyglucose (FDG) has been reported to increase the diagnostic accuracy of subcutaneous metastasis. A 58-year-old woman presented with complaints of dry coughing, in which three positive subcutaneous nodules were found on F-FDG positron emission tom...

© 2009 The Authors. doi: 10.2340/00015555-0584 Journal Compilation © 2009 Acta Dermato-Venereologica. ISSN 0001-5555 Sir, When a subcutaneous mass is noticed in the anterior neck of a patient, we usually consider a diagnosis of skin tumour, lymph node swelling (1), or thyroid tumour (2). Vascular diseases, such as a tortuous major artery, aneurysm, or haemangioma are extremely rare (3–7). We de...

Studies comparing adipose tissue metabolism in central versus peripheral fat depots have generated equivocal data. We examined whether regional differences in abdominal subcutaneous and omental adipose tissue metabolism in women exist and whether they persist across the spectrum of body fatness and abdominal adiposity values. We measured adipocyte size; lipoprotein lipase (LPL) activity; and ba...

disease of unknown cause that can involve various organs. A diagnosis is usually made when clinical and radiological manifestations are supported by histological evidence of the presence of noncaseating granulomas in one or more tissues (1, 2). Sarcoidosis is well characterized by the presence of hilar lymphadenopathy and pulmonary infiltrates. Extrathoracic organs are also involved, such as th...

A 45-year-old lady presented to us with a large subcutaneous swelling on her left side of back of 1 year duration. Local examination revealed a 13×12 cm spherical swelling on the left lower paraspinal region. Magnetic resonance imaging of lumbosacral spine revealed a 13×12 cm mass having solid and cystic components with internal septations in the subcutaneous tissue of left posterior paraspinal...

OBJECTIVE To examine the patterns of growth of visceral fat, subcutaneous abdominal fat, and total body fat over a 3- to 5-year period in white and African American children. RESEARCH METHODS AND PROCEDURES Children (mean age: 8.1 +/- 1.6 years at baseline) were recruited from Birmingham, Alabama, and those with three or more repeated annual measurements were included in the analysis (N = 138...