PURPOSE Postoperative subconjunctival wound healing remains the commonest cause of late bleb failure after glaucoma filtration surgery. This study was undertaken to investigate whether the human monoclonal antibody that neutralizes transforming growth factor-beta2 (CAT-152; lerdelimumab) could be used as a postoperative agent to prevent scarring after glaucoma surgery and compared it with 5-flu...

Subconjunctival emphysema is a condition that must theoretically exist in severe subcutaneous emphysema due to the laxity of the conjunctival tissues. However, this is generally obscured by associated periorbital emphysema and is hidden from view. We present documented evidence of subconjunctival emphysema in the absence of periorbital emphysema. A 53 year old man was admitted with a large righ...

purpose: to report an unusual ocular presentation of a relapse of acute lymphoblastic leukemia. case report: a 9-year-old girl presented with a subconjunctival mass and ipsilateral preauricular lymphadenopathy. she had history of acute lymphoblastic leukemia (all) in remission but had a normal blood cell profile. because of corneal dellen formation and enlargement of the mass over a 2-week peri...

Purpose. To measure the chemotherapeutic effects of focal melphalan (intravitreal and subconjunctival) on tumor burden, hypoxia, and vasculature in LHBETATAG murine retinoblastoma model. Methods. LHBETATAG transgenic mice were treated with a single 1 mcg intravitreal injection of melphalan, 100 mcg subconjunctival injection, or semiweekly 10 mcg subconjunctival injections for 3 weeks. At 1 or 3...

PURPOSE To investigate the immediate effect of intravitreal injection of bevacizumab on intraocular pressure (IOP). METHODS This was a prospective and nonrandomized study. A total of 291 eyes with macular edema or active choroidal neovascularization were submitted to a single 1.25 mg (0.05 mL) bevacizumab intravitreal injection. Intraocular pressure was measured with an Icare(®) tonometer imm...

PURPOSE To evaluate the tear film characteristics of spontaneous subconjunctival hemorrhage patients by Schirmer test I and tear interferometry. METHODS Forty-six spontaneous subconjunctival hemorrhage patients and 46 controls were enrolled in the study. Schirmer test I and tear interferometry were performed in all 92 subjects. The results obtained were compared between the two groups. RESU...

A 55 year old female presented with fever, skin rash and subconjunctival hemorrhage. She also developed hepatitis. Fever and skin rash lasted for more than three weeks. This patient was diagnosed to have rubella, highlighting the fact that rubella can present with atypical features like prolonged fever and rash, subconjunctival hemorrhage and hepatitis, especially in adults.

Objective- To compare the effects of topical eye-drop and subconjunctival administration of diclofenac on improvement of experimental corneal alkali wound in rabbits eyes. Design- Experimental study. Animal- fifteen rabbits. Procedures- Alkali wounds were inflicted on the central corneas of 15 rabbits which we...