Berberis vulgaris and berberine, its main component, traditionally have been used for treatment of various disorders. The pharmacological properties of them have been investigated using different in vivo and in vitro models. In spite of beneficial effects of B. vulgaris on different cell lines, there are documents have revealed negative impacts of it on animal and human. In this regards, the de...

Drug abuse and drug dependence causes drastic medical complications in the body that needs to be averted. New psychoactive drug combinations are emerging globally; pose a severe threat to mankind. An abused formulation sold online under tradename ‘Magic’, was confirmed to containBenzocaine & Caffeine by GC-MS study. In purview of the OECD guidelines, the assessment of sub-chronic& chronic toxic...

in iranian folk medicine, especially in west of the country, the aromatic water of rheum ribes has been used for several purposes such as fever reduction.  despite the widespread use of this plant as food or as a medicinal plant, there is still lack of information on its toxicity profile.                                                                in the present study we aimed to evaluate th...

Silver nanoparticles (Ag NPs) have been widely used as new potent antimicrobial agents in cosmetic and hygienic products. Present study compares the tissue levels of Ag NPs in different organs of Guiana Pigs quantitatively after dermal application and analysis the morphological changes and pathological abnormalities on the basis of the Ag NPs tissue levels. Before toxicological assessments,the...

All aquatic organisms are directly or indirectly affected by the physical characteristics of their environment, especially the chemical composition of the water. The high concentration levels, damage tissues and interfere with the normal growth and proliferation. The aim of this research was to Investigation acute toxicity of ZnSO4 and CuCl2 to Gambusia holbrooki ...

Various studies on Phragmanthera incana (mistletoe) did not intensify toxicity. Toxicological evaluation of Phragmanthera incana, a species of mistletoe growing on two plant hosts namely Cocoa (Theobroma cacao) and Kolanut (Cola nitida) in South-western Nigeria was carried out with the observation of Wistar rats’ haematological and serum biochemical changes for a period of thirty-day administra...