Corynebacterium striatum is a potentially pathogenic microorganism that causes nosocomial outbreaks. However, little is known about its virulence factors that may contribute to healthcare-associated infections (HAIs). We investigated the biofilm production on abiotic surfaces of multidrug-resistant (MDR) and multidrug-susceptible (MDS) strains of C. striatum of pulsed-field gel electrophoresis ...

Statistical learning (SL) is the ability to extract regularities from environment. In domain of language, this fundamental in words and structural rules. lack reliable online measures, statistical word rule have been primarily investigated using offline (post-familiarization) tests, which gives limited insights into dynamics SL its neural basis. Here, we capitalize on a novel task that tracks s...

Embryonic striatal grafts develop a modular organization in which patches of tissue enriched in many transmitter substances characteristic of striatum (P regions) are embedded in surrounds (NP regions) expressing only low levels of these substances. Catecholaminergic fibers from the host brain, identified by their expression of tyrosine hydroxylase (TH), grow into such grafts and selectively te...

We determined mRNA expression of the ionotropic glutamate receptors NMDA (NR1, NR2A and NR2B subunits), AMPA (GluR2 subunit) and kainate (GluR6 subunit), as well as of the glutamate transporters GLAST and GLT1 in cerebral cortex and striatum of wild type (WT) and glutaryl-CoA dehydrogenase deficient (Gchh-/-) mice aged 7, 30 and 60 days. The protein expression levels of some of these membrane p...

Several lines of evidence implicate the striatum in learning from experience on the basis of positive and negative feedback. However, the necessity of the striatum for such learning has been difficult to demonstrate in humans, because brain damage is rarely restricted to this structure. Here we test a rare individual with widespread bilateral damage restricted to the dorsal striatum. His perfor...

The striatum has been shown to be a core region in schizophrenia with functional and structural deficits. Previous studies have confirmed the schizophrenia-related functional connectivity between the striatal and cortical regions. However, among these, few studies have attempted to determine the directional flow of the influence. In the present study, we used resting-state fMRI to explore the d...

Methamphetamine (METH) use results in depletion of monoamines in the striatum. The purpose of this study was to evaluate the relation between the degree of METH-induced monoamine depletion in the striatum and impairment on a striatally-dependent learning task in rats. Male Sprague-Dawley rats received four injections of METH (10 mg/kg) or saline at 2-h intervals. METH treatment produced a 38.5%...

Aging is a process that presents various alterations in physiological, behavioral and neurochemical processes. It causes impairment of CNS functions which lead to changes memory, cognition other performances. Reports have shown aging physiological functions. The aim the present study was evaluate cognitive relation aging. For this 20 male rats were taken, 10 young (4-6 months) old (18-22 months...

Abstract Stimuli previously paired with drugs of dependence can produce cravings that are associated increased dopamine (DA) levels in limbic and striatal brain areas. Positron Emission Tomography (PET) imaging [ 11 C]-(+)-PHNO allows for a sensitive measurement changes DA levels. The purpose the present study was to investigate levels, measured PET C]-(+)-PHNO, regions interest smokers who had...

Corynebacterium striatum is a potentially pathogenic microorganism with the ability to produce outbreaks of nosocomial infections. Here, we document a nosocomial outbreak caused by multidrug-resistant (MDR) C. striatum in Rio de Janeiro, Brazil. C. striatum identification was confirmed by 16S rRNA and rpoB gene sequencing. Fifteen C. striatum strains were isolated from adults (half of whom were...