Background: “Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections”, or PANDAS, is a syndrome characterized by acute-onset obsessive-compulsive disorder (OCD) and/or tics accompanied by the neuropsychiatric symptoms. This case is reported because of its rarity. Case report: A 6.5-year-old boy with swollen tonsils, high-grade fever and rash was admitted to Ami...

Lipids extracted from rabbit skin block the hemolytic capacity of SO and also suppress the neutralizing antibody response to this streptococcal extracellular antigen in rabbith immunized intravenosly. The modification in antibody response is specific for SO; the antibody responses to streptococcal DNase B and to streptococcal NADase are not affected. Cholesterol, a lipid present in abundance in...

Post-streptococcal autoimmunity affects millions worldwide, targeting multiple organs including the heart, brain, and kidneys. To explore the post-streptococcal autoimmunity spectrum, we used western blot analyses, to screen 310 sera from healthy subjects with (33%) and without (67%) markers of recent streptococcal infections [anti-Streptolysin O (ASLO) or anti-DNAse B (ADB)]. A 58 KDa protein,...

OBJECTIVE To determine the short term efficacy and safety of tonsillectomy for recurrent streptococcal pharyngitis in adults. Design Randomised controlled trial. SETTING Academic referral centre in Finland. PARTICIPANTS 70 adults with documented recurrent episodes of streptococcal group A pharyngitis. INTERVENTION Instant tonsillectomy (n=36) or remaining on waiting list as control (n=34)...

Acute streptococcal gingivitis is an acute infection of the oral mucosa. Specific bacterial infections such as to Neisseria gonorrhea, Treponema pallidum, Streptococcal species, and others are very important, but little attention is given to these diseases because they are rarely seen. The purpose of this study was to report the case of an acute streptococcal gingivitis in a patient and to desc...

PURPOSE OF REVIEW Autoimmune disease has long been intertwined with investigations of infectious causes. Antibodies that are formed against an infectious agent can, through the process of molecular mimicry, also recognize healthy cells. When this occurs, the immune system erroneously destroys the healthy cells causing autoimmune disease in addition to appropriately destroying the offending infe...

BACKGROUND The acronym PANDAS (pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections) describes a subgroup of children with obsessive-compulsive disorder and/or tic disorder that experience symptom exacerbations following streptococcal infections. We hypothesized that the prevention of streptococcal infections among children in the PANDAS subgroup would decrea...

Background: In the present study two hundred milk samples were collected from cows and buffaloes with no history of clinical mastitis in ongoing lactation, Sirohi district Southern Rajasthan. Methods: The pooled sample (collected each quarter) examined for status subclinical by Modified California test Somatic cell count respectively. Positive further investigated isolation identification major...

Extracts from 19 of 29 group L streptococcal cultures reacted distinctly with antiserum against group B streptococcal type antigen X in coagglutination and immunodiffusion tests. The X antigen corresponded to those obtained by streptococci of serological groups B and G.