What is Hemochromatosis? Iron storage disease, technically known as hemochromatosis, occurs when too much iron accumulates in the liver and other major organs of the body. The body needs a certain ,amount of iron to produce hemoglobin, which is the means of transporting oxygen molecules from the lungs to all the other cells in the body. However, when too much iron builds up, the body begins to ...

OBJECTIVE Velocity storage mechanism is a multisensory rotation estimator; it compensates for errors in the information provided by the peripheral vestibular organs by means of an adjustment in the duration of the vestibular signal. The aim of this study was to determine the activity of the velocity storage mechanism in the presence of a labyrinthine disorder, using galvanic vestibular stimulat...

Obesity and lack of physical activity are two major factors contributing considerably to the pathogenesis of many chronic diseases so prevalent in contemporary human population. Adipose tissue and skeletal muscle are therefore the primary organs one would immediately suggest to target in an attempt to battle metabolic disease progression. Fine tuning of the physiological processes within the tw...

Though endopeptidases and carboxypeptidases are present in protein bodies of dry quiescent seeds the function of these proteases during germination is still a matter of debate. In some plants it was demonstrated that endopeptidases of dry protein bodies degrade storage proteins of these organelles. Other studies describe cases where this did not happen. The role that stored proteinases play in ...

Understanding the relationships between biochemical contents and morpho-phenological aspects of a plant during life cycle would be helpful for doing precise agricultural practices through its cultivation. In the present study, various biochemical parameters were evaluated in relation to bulb storage, shoot growth and florogenesis in Iranian lily (Lilium ledebourii var. Kelardasht Salehi1). Ten ...

Ticks are obligate hematophagous parasites and important vectors of diseases. The large amount of blood they consume contains great quantities of iron, an essential but also toxic element. The function of ferritin, an iron storage protein, and iron metabolism in ticks need to be further elucidated. Here, we investigated the function a newly identified secreted ferritin from the hard tick Haemap...

Mucopolysaccharidosis I (MPS I) due to deficient alpha-L-iduronidase (IDUA) activity results in accumulation of glycosaminoglycans in many cells. Gene therapy could program cells to secrete IDUA modified with mannose 6-phosphate (M6P), and enzyme could be taken up by other cells via the M6P receptor. We previously reported that newborn MPS I mice that were injected intravenously with 10(9) (hig...