Clathrin-mediated endocytosis is involved in the internalization, recycling, and degradation of cycling membrane receptors as well as in the biogenesis of synaptic vesicle proteins. While many constitutively internalized cargo proteins are recognized directly by the clathrin adaptor complex AP-2, stimulation-dependent endocytosis of membrane proteins is often facilitated by specialized sorting ...

Greenstone and DSpace are widely used software systems for digital libraries, and prospective users sometimes wonder which one to adopt. In fact, the aims of the two are very different, although their domains of application do overlap. This article describes the two systems and identifies their similarities and differences. We also present StoneD [note 1] a bridge between the production version...

INTRODUCTION Acute intoxications become more and more a serious problem in developing countries. However, epidemiologic data are very scarce in these countries. OBJECTIVE To describe the characteristics of acute intoxications in two University Hospitals of Ouagadougou (Burkina Faso). METHODS All cases admitted to the emergency services of the two sole University Hospitals of Ouagadougou fro...

Accidental exposure to uranium is a matter of concern, as U(VI) is nephrotoxic in both human and animal models, and its toxicity is associated to chemical toxicity instead of radioactivity. We synthesized different PAMAM G4 and G5 derivatives in order to prove their interaction with uranium and their effect on the viability of red blood cells in vitro. Furthermore, we prove the effectiveness of...

In the present work, we report the determination of phenolic compounds in 'alcaparra' table olives by reversed-phase HPLC/DAD, and the evaluation of their extract in vitro activity against several microorganisms that may be causal agents of human intestinal and respiratory tract infections, namely Gram positive (Bacillus cereus, Bacillus subtilis, and Staphylococcus aureus), Gram negative bacte...

With legal cannabis sales at $5.4 billion in 2015 and expected to rise by another billion this year in the United States, legalization and marijuana's impact on health is a hot topic of national debate. Casarett, a physician at the University of Pennsylvania, immerses himself in the culture, science, and smoke of medical marijuana in order to sort out the truth behind the buzz. Our reviewer, wh...

Aman in Mexico is fired after he develops tuberculosis and fellow workers fear that he may be HIV-positive. A pregnant woman in Ukraine learns of her HIV status during delivery and healthcare workers coerce her into being sterilized after giving birth. In Cambodia, community members avoid the local temple when the monks there begin providing support to AIDS orphans. In-laws steal a woman’s prop...

Abstract In the last decades, there has been a growing interest in measuring efficiency of hospitals using different methodological approaches, mainly represented by data envelopment analysis (DEA) and stochastic frontier (SFA). this study, we estimate measures performance for sample Panamanian public over an 11‐year period (2005–2015) both traditional methods (DEA SFA) compare them with effici...