OBJECTIVE To assess whether intermittent transdermal treatment with glyceryl trinitrate causes clinically significant rebound in patients maintained on beta blockers for stable angina pectoris. DESIGN Serial treadmill exercise testing in a double blind, randomised, placebo controlled cross over trial. Baseline exercise testing was performed at 0900 and 1100 at visit 1. Transdermal glyceryl tr...

OBJECTIVE To use intravascular ultrasound (IVUS) to compare plaque morphology in acute myocardial infarction and stable angina pectoris. DESIGN Retrospective study. SETTING Primary care hospital. PATIENTS 59 consecutive cases of acute myocardial infarction and 50 consecutive cases of stable angina pectoris. METHODS IVUS was used before coronary intervention. MAIN OUTCOME MEASURES Plaq...

The fractal scaling properties of the heartbeat time series are studied in a controlled ergometric regime using the Hurst rescaled range R/S analysis. The long-time ”memory effect” quantified by the value of the Hurst exponent H > 0.5 is found to increase during progresive physical activity at healthy subjects in contrast to those having stable angina pectoris (SAP), where it is decreasing. We ...

The number of drugs available for treatment of angina pectoris has increased dramatically in recent years; new beta and calcium channel blockers are to be introduced; nitrates are now available in transdermal pads and could become released as buccal tablets or aerosol sprays. A broad understanding of the pharmacological principles of their use is necessary to tailor therapy for each patient.

Symptoms play a crucial part in the formulation of medical diagnoses, yet the construction and interpretation of symptom narratives is not well understood. The diagnosis of angina is largely based on symptoms, but a substantial minority of patients diagnosed with "non-cardiac" chest pain go on to have a heart attack. In this ethnographic study our aims were to understand: (1) how the patients' ...

The aim of our study was to improve the treatment of patients with stable Angina Pectoris functional class III with Hypertension and prevention of nitratoresistance development with usage of antioxidant (Mexicor) and NO-donor (L-arginine). The study involved 63 patients with stable angina pectoris FC III with concomitant Hypertension. All patients were divided into two groups. Patients of I gro...

congenital anomalies of coronary arteries, albeit rare, may be significant contributors to angina pectoris, hemodynamic abnormalities, and sudden cardiac death. a 47-year-old man referred to us with atypical chest pain. electrocardiography demonstrated no significant ischemic changes, but cardiac troponin i test was positive. the patient underwent coronary angiography, which revealed a single c...

discussion hydatid cyst in pericardium represents only 0.5-2% of cases of systemic echinoccocal infection. isolated pericardial cyst is very rare in endemic region and may present mimicking acute coronary syndrome. cardiac hydatid cysts should always be considered in presence of eosinophilia as present like acute coronary syndrome in endemic area. introduction hydatid cysts are most commonly fo...

AIMS Serum levels of neopterin, an immune modulator secreted by activated macrophages, are elevated in patients with acute coronary syndromes compared with stable angina patients and control subjects. In unstable angina, serum neopterin levels correlate with the presence of vulnerable coronary stenosis, multiple complex coronary lesions, and patient outcome. The present study assessed the progn...

The first 840 consecutive patients who underwent percutaneous transluminal coronary angioplasty (PTCA) performed in the same institution were retrospectively assessed at an average follow-up period of 25 months after the initial procedure. The study population consisted of 506 patients with stable angina pectoris (group 1) and 334 patients with unstable angina pectoris (group 2). Clinical end p...