This paper estimates investment cost targets for future nuclear power plants to be competitive in mid-21st century energy markets and beyond. The point of departure is the nuclear market shares derived from the Special Report on Emissions Scenarios (SRES) of the Intergovernmental Panel on Climate Change. One provocative result is that substantial nuclear expansion does not seem to require big r...

The study aimed to find out possible changes in climatic data (temperature and rainfall) from the regional climate model viz. PRECIS(Providing Regional Climates for Impact Studies)under different SRES scenarios (A1B, A2 B2 scenario) by mid (2021-2050) end (2071-2100) century at six locations of Punjab representing agroclimatic zones their impact on maize yield using crop growth simulation model...

BACKGROUND Bisphosphonates, which are also known as osteoclast modifiers, are the standard of care in the treatment of skeletal-related events (SREs) in patients with breast cancer with metastatic bone disease. SREs are frequently a complication of advanced breast cancer, and they greatly increase morbidity and mortality in these patients. Unfortunately, even while undergoing bisphosphonate the...

This paper reviews the health dimension and sociocultural, economic, and ecological determinants of health in existing global scenario studies. Not even half of the 31 scenarios reviewed gave a good description of future health developments and the different scenario studies did not handle health in a consistent way. Most of the global driving forces of health are addressed adequately in the se...

The purpose of this study was to estimate the risk of developing skeletal-related events (SREs) based on site of metastasis at diagnosis and identify other predictors of developing SREs among metastatic prostate cancer patients. We conducted a retrospective cohort study using linked SEER (Surveillance, Epidemiology, and End Results) and Medicare data and identified men over the age of 65 with i...

Shifts in temperature and precipitation patterns caused by global climate change may have profound impacts on the ecology of certain infectious diseases. We examine the potential impacts of climate change on the transmission and maintenance dynamics of dengue, a resurging mosquito-vectored infectious disease. In particular, we project changes in dengue season length for three cities: Atlanta, G...

In letters sent to the IPCC Chairman, Dr. Pachauri, in August 2002, I criticised the use in the IPCC Special Report on Emissions Scenarios (SRES) of nominal exchange rates, rather than purchasing power parity rates, for expressing the GDP of different countries in a common unit of measurement. My letters acknowledged that there are large differences in income per capita between countries and re...

BACKGROUND Skeletal-related events (SREs; pathologic fracture, radiation or surgery to bone, spinal cord compression) frequently occur in patients with advanced cancer with bone metastases/lesions. Limited data on the associated patient and economic burden are available to aid in resource planning and evaluating treatment options. METHODS Patients with bone metastases/lesions secondary to bre...

This paper analyzes a set of global energy-economic development scenarios for the 21" century. The set includes non-climate-policy scenarios that are part of the recent Special Report on Emissions Scenarios (SRES) of the Intergovernmental Panel on Climate Change (IPCC). We apply climate policies to some of these scenarios to achieve stabilization of atmospheric C02 concentrations at 550 parts p...

Synthetic biology (SB) applies engineering principles to biology for the construction of novel biological systems designed for useful purposes. From an oversight perspective, SB products come with significant uncertainty. Yet there is a need to anticipate and prepare for SB applications before deployment. This study develops a Societal Risk Evaluation Scheme (SRES) in order to advance methods f...