نتایج جستجو برای: spirolactone

تعداد نتایج: 64  

In this paper, a new nano-size ionic liquid (nIL) has been synthesized from D-phenylalanine and oxalic acid (D-Phe-OX) via a simple procedure. The obtained nIL has been characterized by the fourier transform infrared spectroscopy (FT-IR), energy-dispersive X-ray spectroscopy (EDAX), thermogravimetric analysis (TGA), nuclear magnetic resonance spectroscopy (1</sup...

2012
Renato L. Carneiro Ronei J. Poppi

Neste trabalho, a espectroscopia de imagens no infravermelho próximo (NIR) foi empregada no estudo da distribuição do princípio ativo (API) espironolactona e seus excipientes em comprimidos. As análises foram realizadas utilizando resolução espacial de 50 μm, analisando 16 mm de cada comprimido padrão. Modelos de mínimos quadrados parciais por intervalo (iPLS) foram utilizados para quantificaçã...

1999
Longmei Zeng Jingyu Su Yongli Zhong Xiong Fu Tangsheng Peng Ye Zhu Yanhui Meng Yingzhou Cen Xiaohua Xu Yaohua Zheng Guiyangsheng Wang

In search of new pharmaceutically valuable substances from marine organisms, we have been engaged in chemical studies on the constituents of corals, sponges and algae collected in the South China Sea. This paper summarizes some of our research results. Terpenes, nitrogen-containing compounds and polyhydroxylated sterols are mainly discussed. The corals, marine sponges and algae are abundant nat...

2001
PHILIPPE NIRDÉ BÉATRICE TÉROUANNE NADINE GALLAIS CHARLES SULTAN GILLES AUZOU

In humans, spironolactone and mespirenone are well known antimineralocorticoids without C-11b substituents. These compounds display antagonist properties by acting through the human androgen receptor (hAR). In contrast, we demonstrate here that synthetic mineralocorticoid antagonists bearing hydrophobic C-11b substituents and C-17g-lactone are potent hAR agonists in vitro. The three-dimensional...

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