نتایج جستجو برای: spindles

تعداد نتایج: 3769  

Journal: :Investigative ophthalmology & visual science 1999
R Blumer J R Lukas M Aigner R Bittner I Baumgartner R Mayr

PURPOSE To clarify whether structural peculiarities formerly described in extraocular muscle (EOM) spindles of aged persons are already present in EOM spindles of a 2-year-old infant. METHODS Distal halves of two EOMs obtained from a 2-year-old multiorgan donor were immersion-fixed and prepared for electron microscopy. The fine structure of 10 muscle spindles and of 1 "false spindle" was inve...

Journal: :Current Biology 2000
James G. Wakefield Jun-yong Huang Jordan W. Raff

We reported previously that the disappearance of cyclin B at the end of mitosis in early Drosophila embryos starts at centrosomes and spreads into the spindle [1]. Here, we used a novel mutation, centrosome fall off (cfo), to investigate whether centrosomes are required to initiate the disappearance of cyclin B from the spindle. In embryos laid by homozygous cfo mutant mothers, the centrosomes ...

Journal: :Journal of cognitive neuroscience 2017
Zhuo Fang Valya Sergeeva Laura B. Ray Jeremy Viczko Adrian M. Owen Stuart M. Fogel

Sleep spindles-short, phasic, oscillatory bursts of activity that characterize non-rapid eye movement sleep-are one of the only electrophysiological oscillations identified as a biological marker of human intelligence (e.g., cognitive abilities commonly assessed using intelligence quotient tests). However, spindles are also important for sleep maintenance and are modulated by circadian factors....

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2002
Hsiao-Huei Chen Warren G Tourtellotte Eric Frank

Ia afferents induce the formation of muscle spindles prenatally and maintain them postnatally. To address whether spindles, in turn, regulate the function of Ia afferents, we examined Egr3-null mutant mice (Egr3-/-), in which muscle spindles degenerate progressively after birth. Egr3-/- mice develop gait ataxia, scoliosis, resting tremors, and ptosis, suggesting a defect in proprioception. Desp...

Journal: :Journal of the Textile Machinary Society 1958

1997
D. CONTRERAS A. DESTEXHE

Spindling activity characterizes the EEG of animals and humans in the early stages of resting sleep. Spindles are defined as waxing and waning rhythmic waves at 7–14 Hz that recur periodically every 3–10 s. Spindling originates in the thalamus, but a role for the cerebral cortex in triggering and synchronizing thalamic spindles was shown by stimulation of the contralateral cortex avoiding antid...

2016
Rafael Toledo Fernandes de Souza Günther Johannes Lewczuk Gerhardt Suzana Veiga Schönwald José Luiz Rybarczyk-Filho Ney Lemke

Sleep spindles occur thousands of times during normal sleep and can be easily detected by visual inspection of EEG signals. These characteristics make spindles one of the most studied EEG structures in mammalian sleep. In this work we considered global spindles, which are spindles that are observed simultaneously in all EEG channels. We propose a methodology that investigates both the signal en...

2015
Dina Radovanovic Kevin Peikert Mona Lindström Fatima Pedrosa Domellöf

The aim of the present study was to investigate the presence of sympathetic innervation in human muscle spindles, using antibodies against neuropeptide Y (NPY), NPY receptors and tyrosine hydroxylase (TH). A total of 232 muscle spindles were immunohistochemically examined. NPY and NPY receptors were found on the intrafusal fibers, on the blood vessels supplying muscle spindles and on free nerve...

Journal: :Journal of cell science 1987
R C Brady M J Schibler J R Dedman F Cabral

Mitotic spindles were isolated from Chinese hamster ovary (CHO) cells and examined morphologically and biochemically. The isolated spindles were observed to be intact structures containing associated chromosomes and were surrounded by a cage of vimentin-containing filaments. Two-dimensional gel electrophoresis of isolated spindles versus whole cell homogenates indicated that isolated spindles w...

Journal: :Developmental cell 2018
Zan Tang Yucheng Hu Zheng Wang Kewu Jiang Cheng Zhan Wallace F Marshall Nan Tang

Oriented cell division plays a key role in controlling organogenesis. The mechanisms for regulating division orientation at the whole-organ level are only starting to become understood. By combining 3D time-lapse imaging, mouse genetics, and mathematical modeling, we find that global orientation of cell division is the result of a combination of two types of spindles with distinct spindle dynam...

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