Acute experimental allergic neuritis was induced in Lewis rats by inoculation with bovine intradural root myelin and adjuvants. In terminal experiments, sensory conduction was assessed in rats with hindlimb ataxia and weakness by stimulating the exposed sciatic nerve and recording directly from the exposed L-4 spinal nerve, dorsal root ganglion, dorsal root, and dorsal root entry zone. Focal co...

OBJECT The pathogenesis of syringomyelia in patients with an associated spinal lesion is incompletely understood. The authors hypothesized that in primary spinal syringomyelia, a subarachnoid block effectively shortens the length of the spinal subarachnoid space (SAS), reducing compliance and the ability of the spinal theca to dampen the subarachnoid CSF pressure waves produced by brain expansi...

R E P L Y Thank you for giving us the opportunity to respond to Dr. Fortuna's comments. It is possible that apnoea in this patient can partly be from hypotension and brainstem hypoperfusion, but she did develop flaccid paralysis in her upper extremities which means that motor paralysis in the cervical region had, indeed, taken place. The block, however (both sensory and motor), started regressi...

Slow resolution of block and incidence of side effects deter many practitioners from choosing spinal anesthesia for out-patient surgical procedures. Some studies suggest that controlling bevel or side port orientation of a spinal needle during anesthetic injection can affect occurrence of side effects and time to block resolution. The objective of this study was to determine the effects of vary...

BACKGROUND AND OBJECTIVES Unilateral spinal anesthesia may be advantageous, especially in the outpatient setting. Low local anesthetic doses, slow spinal injection rate and the lateral position have been related to the easiness of inducing unilateral spinal anesthesia. This study aimed at investigating the possibility of inducing unilateral spinal anesthesia with isobaric 0.5% bupivacaine. ME...

BACKGROUND AND OBJECTIVES Spinal block is commonly used in cesarean sections and, if some prophylactic measures are not taken, the incidence of hypotension is higher than 80%. The objective of this study was to compare the efficacy of the administration of therapeutic or prophylactic doses of phenylephrine to maintain blood pressure in patients undergoing spinal block for elective cesarean sect...

Because of the frequency of multiple sites of involvement, a thorough evaluation of the entire spinal canal is essential for detection and treatment of spinal compression in cancer patients. For the examination of the entire spinal canal in cancer patients, a modified approach is described using water-soluble contrast medium (metrizamide), oil-based material (Pantopaque), and a "squeezing" tech...

BACKGROUND Unilateral spinal anesthesia is performed to provide restriction of sensory and motor block. OBJECTIVE The aim of this study was to compare unilateral and bilateral spinal anesthesia, with regard to limiting the nerve block exclusively to the area of surgery. METHODS This was a prospective, randomised, double-blind study, conducted in 40 consecutive outpatients scheduled for unil...

Objective: This study was designed to compare the effects of equivalent doses of bupivacaine and levobupivacaine on propofol requirement in BIS guided sedation under spinal anesthesia. Material and Methods: Spinal anesthesia was performed on seventy patients scheduled for elective lower limb surgery with 3 mL’s of either isobaric bupivacaine (Group B) or plain levobupivacaine (Group L). Five mi...