This work demonstrates the preparation of spherical nanocellulose from microcrystalline cellulose by controlled hydrolysis using anaerobic microbial consortium. The nanocellulose formed during the degradation of microcrystalline cellulose was separated by ultra filtration membrane and purified by differential centrifugation. The purified nanocellulose was characterized by nanoparticle size anal...

Adhesion of micro and nanoparticles onto cardiovascular walls is a critical process in applications such as targeted drug delivery, biomedical imaging, and cancer treatment. This paper intends to develop an understanding of the dynamic interaction between particle and vessel wall through computational modeling. The ligand-receptor binding dynamics is coupled with Immersed Finite Element Method ...

The use of polymeric nanoparticles as drug delivery devices is becoming increasingly prevalent in a variety of therapeutic applications. Despite their widespread clinical use, the factors influencing the release profiles of nanoparticle-encapsulated drugs are still not quantitatively understood. We present here a new, semi-empirical model of drug release from polymeric nanoparticles using a for...

Coherent potential approximation is used to study the effect of adding doped spherical nanoparticles inside a host matrix on the thermoelectric properties. This takes into account electron multiple scatterings that are important in samples with relatively high volume fraction of nanoparticles (>1%). We show that with large fraction of uniform small size nanoparticles (∼1 nm), the power factor c...

We have utilized 2D material point method (MPM) to study the influence of nanoparticles on the diffusivity of penentrants in model polymer membranes comprised of impenetrable spherical nanoparticles dispersed in a matrix with uniform penetrant solubility and diffusivity. The polymer membrane near the surface of a nanoparticle exhibits enhanced penetrant diffusion relative to that of the bulk po...

Multi-color gold-nanoparticle-based tags (nanotags) are synthesized for combined surface-enhanced Raman spectroscopy (SERS) and x-ray computed tomography (CT). The nanotags are synthesized with quasi-spherical gold nanoparticles encoded with a reporter dye (color), each with a unique Raman spectrum. A library of nanotags with six different colors were synthesized for a range of gold nanoparticl...

The optical properties of alternating ultrathin Ti0.91O2 nanosheets and CdS nanoparticle hybrid spherical structures designed by the layer-by-layer (LBL) assembly technique are investigated. From the photoluminescence (PL) spectral measurements on the hybrid spherical structures, a spectrum-shifted fluorescence emission occurs in this novel hybrid material. The time-resolved PL measurements exh...

First-principles calculations are performed to obtain the dielectric function and loss spectra of bulk PdH(x). Hydrogen concentrations between x = 0 and 1 are considered. The calculated spectra are dominated by a broad peak that redshifts in energy with x. The obtained bulk dielectric function is employed to compute the loss spectra of PdH(x) spherical nanoparticles as a function of x. The domi...

In this work, a new algorithm is proposed to compute single particle (infinite dilution) thermodiffusion using nonequilibrium molecular dynamics simulations through the estimation of the thermophoretic force that applies on a solute particle. This scheme is shown to provide consistent results for model nanofluids in the liquid state (spherical nonmetallic nanoparticles+Lennard-Jones fluid) wher...

The surface energy density of nano-sized elements exhibits a significantly size-dependent behavior. Spherical nanoparticle, as an important element in nano-devices and nano-composites, has attracted many interesting studies on size effect, most of which are molecular dynamics (MD) simulations. However, the existing MD calculations yield two opposite size-dependent trends of surface energy densi...