This Supplement is organized as follows: The climate model is described in detail in section 1. Section 2 discusses the robustness of multiple subpolar gyre (SPG) modes by presenting findings from several climate models. Section 3 continues this discussion summarizing work on the sensitivity of the SPG primarily in CLIMBER3α. This is followed by figures supporting conclusions in the main text a...

Pulse wave transmit time method has been used to estimate blood pressure by simultaneously measuring electrocardiogram & pulse signals [1]. Most researchers use photo reflective sensor to capture photoplethysmograph (PPG) signal by attaching sensor on finger tip. However, such a way would interfere hands in operating further the e-home healthcare system, plus PPG has flatter morphological shape...

Symmetrical peripheral gangrene (SPG) is a rare clinical entity, infective, and noninfective both types of etiologies are responsible. The basic underlying pathology in SPG is being disseminated intravascular coagulation and carries a high mortality. Here, we describe a 52-year-old male with dengue fever, who developed bilateral symmetrical dry gangrene of both hand and feet. His dengue IgM ant...

Background: Patients with cancer treatment-related cardiotoxicity, which may manifest as heart failure (HF), can present with dyspnea. Nurses frequently assess, triage and offer self-care strategies to patients experiencing dyspnea in both the cardiology and oncology settings. However, there are no known tools available for nurses to manage patients in the setting of cancer treatment-related ca...

Cluster headache is a devastating primary headache disorder (1) that in its chronic form presents as if approached and consumed by three beasts. Medically intractable chronic cluster headache (2) is among the most challenging of ailments headache specialists can be called on to treat. While we have seen important advances in understanding the disorder with brain imaging (3,4), and the conduct o...

BACKGROUND The sphenopalatine ganglion (SPG) is located with some degree of variability near the tail or posterior aspect of the middle nasal turbinate. The SPG has been implicated as a strategic target in the treatment of various headache and facial pain conditions, some of which are featured in this manuscript. Interventions for blocking the SPG range from minimally to highly invasive procedu...

In this paper we introduce semi-pseudo-ovoids, as generalizations of the semi-ovals and semi-ovoids. Examples of these objects are particular classes of SPG-reguli and some classes of m-systems of polar spaces. As an application it is proved that the axioms of pseudo-ovoid O(n, 2n, q) in PG(4n − 1, q) can be considerably weakened and further a useful and elegant characterization of SPG-reguli w...

PURPOSE The purpose of this investigation was to compare the accuracy of facial models fabricated using facial moulage impression methods to the three-dimensional printed (3DP) fabrication methods using soft tissue images obtained from cone beam computed tomography (CBCT) and 3D stereophotogrammetry (3D-SPG) scans. MATERIALS AND METHODS A reference phantom model was fabricated using a 3D-SPG ...

Objectives The sphenopalatine ganglion (SPG) plays a pivotal role in cluster headache (CH) pathophysiology as the major efferent parasympathetic relay. We evaluated the long-term effectiveness of SPG stimulation in medically refractory, chronic CH patients. Methods Thirty-three patients were enrolled in an open-label follow-up study of the original Pathway CH-1 study, and participated through 2...

Silencing Y-box binding protein 1 (YB-1) can be an excellent target for cancer therapy and many lung cancer cells express the polysaccharide-recognition receptor Dectin-1. We designed a Dectin-1 targeting vehicle delivering YB-1-antisense DNA. First, we selected five optimal antisense DNA sequences to silence YB-1 from among 153 candidates. We chose the sequence closest to the start codon (AS01...