The present study describes integron mediated multiple antibiotic resistance in extended-spectrum β-lactamase producing clinical isolates of Klebsiella pneumoniae. One hundred and four clinical isolates of K. pneumoniae from two Iranian hospitals were screened for extended-spectrum β-lactamase production and susceptibility of the extended-spectrum β-lactamase producing isolates was determined t...

background beta-lactam resistance in gram-negative bacteria, especially escherichia coli, is a main clinical problem. it is often caused by the co-production of β-lactamases, particularly extended-spectrum β-lactamases (esbls) and ampc enzymes. it may lead to a problem for diagnosis via recommended phenotypic tests by the clinical and laboratory standards institute (clsi). conversely, β-lactama...

S. S. Masood,1,* S. Nasri,2,† J. Schechter,3,‡ M. A. Tórtola,4,§ J. W. F. Valle,5,‖ and C. Weinheimer6,¶ 1Department of Physics, 2700 Bay Area Boulevard, University of Houston Clear Lake, Houston, Texas 77058, USA 2Institute for Fundamental Theory, University of Florida, Gainesville, Florida, USA 3Department of Physics, Syracuse University, Syracuse, New York 13244-1130, USA 4Departamento de Fı́...

land. Furthermore, Ct. felis often feeds on humans. Clinicians encountering patients with fever or rash (or both) and a history of cat contact or flea bites should consider a diagnosis of R. felis. Laboratory confirmation of infection is not easy, but in vitro culture of R. felis, and hence material for a serologic assay for the diagnosis of human R. felis infections, has recently been describe...

Resistance to β-lactams is constantly increasing due to the emergence of totally new enzymes but also to the evolution of preexisting β-lactamases. GES-1 is a clinically relevant extended-spectrum β-lactamase (ESBL) that hydrolyzes penicillins and broad-spectrum cephalosporins but spares monobactams and carbapenems. However, several GES-1 variants (i.e., GES-2 and GES-5) previously identified a...

It has been shown that the single-point probability density functions of the data of certain cloud properties, such as cloud optical depth, are positively skewed and resemble the probability density functions of a log-normal random variable (e.g. Barker et al., 1996). There is also evidence that, for certain spatial scales, the two-point statistics are such that the energy spectrum Ek satisfies...

www.expert-reviews.com ISSN 1478-7210 © 2008 Expert Reviews Ltd 10.1586/14787210.6.5.671 The potential options available for treating serious infections caused by enterobacteria include penicillins (with or without β-lactamase inhibitors), cephalosporins, aztreonam, carbapenems, fluoroquinolones and, in certain situations only, aminoglycosides and colistin. Recently, tigecycline has been added ...

For an operator, A, with cyclic vector φ, we study A+ λP where P is the rank one projection onto multiples of φ. If [α,β] ⊂ spec(A) and A has no a.c. spectrum, we prove that A + λP has purely singular continuous spectrum on (α, β) for a dense Gδ of λ’s. §

Carbapenems are frequently used for severe hospital infections caused by K. pneumoniae, especially when isolates produce extended-spectrum β-lactamases...