The spectrophotometric method described is quick and effective and a reliable alternative to a titrimetric method for measuring trypsin activity in duodenal juice.

Literature survey reveals that few analytical methods were reported for the estimation of cinacalcet hydrochloride by LC, UV methods. Hence the present study aims in developing simple, rapid, precise and validated methods for cinacalcet hydrochloride in bulk. The methods are Colorimetric determination of Cinacalcet Hydrochloride by Visible Spectrophotometric method, Validation of Cinacalcet Hyd...

In this study, a high-performance liquid chromatographic method (HPLC) and UV spectrophotometric method were developed, validated and applied for the determination of theophylline in biological fluids. Liquid- liquid extraction is performed for isolation of the drug and elimination of plasma and saliva interferences. Urine samples were applied without any extraction. The chromatographic separat...

During the investigation of aviation accidents, postmortem samples from accident victims are submitted to the FAA's Civil Aerospace Medical Institute for toxicological analysis. In order to determine if an accident victim was exposed to an in-flight/postcrash fire or faulty heating/exhaust system, the analysis of carbon monoxide (CO) is conducted. Although our laboratory predominantly uses a sp...

This study reports an improved spectrophotometric method for studying bacterial (Pseudomonas fluorescens UPER-1) transport and attachment in saturated porous media (silica sand). While studying the effect of ionic strength by the traditional packed-column spectrophotometric method, we encountered an artifact. The absorbance of a well-stirred bacterial suspension was found to decrease with time ...

The most common spectrophotometric reagents employed for the determination of titanium (IV) are hydrogen peroxide[1] and tiron[2]. However, N-benzoylN-phenylhydroxylamine[3,4] and N-phenyllaurohydroxamic acid[5] are introduced for extractive spectrophotometric determination of titanium (IV). Aroylhydraones such as pyridoxal salicyloylhydrazone[6], diphenylglyoxal bis (benzoylhydrazone)[7] and d...

This paper describes zeroand first-order derivative spectrophotometric methods for determination of estradiol valerate in pharmaceutical preparations. The solutions of the standard and pharmaceutical samples were prepared in methanol. Absorbances of estradiol valerate were measured at 280 nm for zero-order by measuring height of peak from zero, at 292 nm for first-order derivative spectrophotom...

Simple, fast and reliable derivative spectrophotometric methods were developed for determination of olanzapine in bulk and pharmaceutical dosage forms. The solutions of standard and the sample were prepared in methanol. The quantitative determination of the drug was carried out using the first derivative values measured at 222 nm and the second derivative values measured at 230 nm (n=6). Calibr...

PURPOSE An accurate and precise UV spectrophotometric method with multivariate calibration technique for the determination of aripiprazole in pharmaceutical formulations has been described. METHODS This technique is based on the use of the linear regression equations by using the relationship between concentration and absorbance at five different wavelengths. The aripiprazole shows absorption...

A method is proposed for automatic instrumentation of enzyme activity determinations which involve spectrophotometric measurements. The procedure utilizes a kinetic method to produce one instrumental reading that is proportional to enzyme concentration. The single spectrophotometric reading can be processed by analog or digital computation, using the known absorptivity constant of the reactant ...