In single photon emission computed tomography (SPECT), pinhole and cone-beam collimators are used for small object imaging. It is accepted that a pinhole collimator should be used if the object is very small, and the cone-beam collimator should be used if the object is larger. This paper presents criteria to determine which collimation geometry is more advantageous in terms of spatial resolutio...

Because background radiation in an irradiation room creates a problem with the PG-SPECT (Prompt Gamma-ray Single Photon Emission Computed Tomography) system, which evaluates the absorbed dose for the Boron Neutron Capture Therapy treatment, optimization of a collimator system was performed while taking the shielding of background gamma-rays into consideration. Assuming that a parallel-beam coll...

introduction:it is well-recognized that collimator-detector response (cdr) is the main image blurring factor in spect.  in this research, we compensated the images for cdr in molecular spect by using stir reconstruction framework. methods: to assess resolution recovery capability of the stir, a phantom containing five point sources along with a micro derenzo phantom were investigated. influence...

In this paper, we will report the development of an ultrahigh resolution MR-compatible SPECT system that can be operated inside a pre-existing clinical MR scanner for simultaneous dual-modality imaging of small animals. This system is constructed with 40 small-pixel CdTe detector modules assembled in a fully stationary ring SPECT geometry. We have experimentally demonstrated that this system is...

BACKGROUND Obtaining high quality images in Single Photon Emission Tomography (SPECT) device  is the most important goal in nuclear medicine. Because if image quality is low, the possibility of making a mistake in diagnosing and treating the patient will rise. Studying effective factors in spatial resolution of imaging systems is thus deemed to be vital. One of the most important factors in SPE...

UNLABELLED Ex vivo measurements in animals are used frequently in the field of nuclear medicine for the characterization of newly developed radioligands and for drug development. In vivo SPECT would replace these ex vivo measurements in a relatively large number of cases if one were able to adequately image small organs. The pinhole collimator has been used extensively to obtain greater detail ...

UNLABELLED The Inveon small-animal SPECT system comes with several types of multipinhole collimator plates. We evaluate here the performance measurements of the Inveon SPECT system using 6 different collimators: 3 dedicated for mouse imaging and 3 for rat imaging. METHODS The measured performance parameters include the sensitivity, the spatial resolution using line sources, the ultra-micro De...

Purpose: We had previously shown the MR compatibility of CZT based single photon detectors and associated nuclear data acquisition electronics [1]. The purpose of the present work was to study the feasibility a combined MRSPECT system operating inside a 4T MR system for dual-modality MR-SPECT imaging. The current investigation included a study of the effect of SPECT detector/collimator system o...

UNLABELLED The objective of this study, which is related to human brain SPECT, was to increase the sensitivity of a triple-camera SPECT system and reduce statistical noise in reconstructed images using a combination of converging collimators. The reason for combining collimators is to ensure both high sensitivity and sufficient sampling without trading off spatial resolution. METHODS A high-s...