studies have shown that patients who do not produce donor specific and / or panel reactive anti-hla antibodies have a longer graft survival. the purpose of this study was to evaluate the posttransplant humoral immune response towards hla-class i antigens and the measurement of the serum creatinine levels which are used in monitoring posttransplant function of kidney. serum samples from 132 rena...

Cyclosporin A (CsA) is currently the most selective immunosuppressant used clinically to prevent organ rejection after transplantation. We used a reprogrammable robot, the Benchmate (Zymark Inc., Hopkinton, MA), to automate much of the sample preparation involved in solid-phase extraction of CsA. Lysed whole-blood specimens containing previously added internal standard were placed on the Benchm...

Cuckoo hosts defend themselves against parasitism by means of mobbing, egg rejection, and chick rejection. However, each of these defenses is prone to costly recognition errors, and hosts are therefore more likely to deploy these defenses if they observe a cuckoo in the vicinity of their nest. The success of such response plasticity depends on accurate recognition of sympatric cuckoo species, b...

For biodiversity research, the field of study that is concerned with the biological diversity of our planet, it is of utmost importance that the location of an animal specimen find is known with high precision. Due to specimens often having been collected over the course of many years, their accompanying geographical data is often ambiguous or may be very imprecise. In this contribution, we det...

PURPOSE The purpose of this study is to report a case of microsporidial endophthalmitis after penetrating keratoplasty in a healthy patient and discuss the management. METHODS This is a case report. RESULTS A 69-year-old healthy male underwent penetrating keratoplasty for corneal scar secondary to herpes stromal keratitis. He presented with features of acute graft rejection 3 years later. A...

In conventional microscopes, fluorescence emission is separated from the backscattered illumination using the Stokes shift, whereby the emission occurs at a longer wavelength to the excitation. Such separation is usually achieved through a combination of wavelength filters that divide the spectrum into mutually exclusive excitation and emission bands. It is therefore impossible in these microsc...

Cyclosporin-A (CsA) and tacrolimus (FK-506) are immunomodulating agents used to prevent rejection in organ transplantation. They are both associated with several side effects, including nephrotoxicity and severe hypertension due to vascular injury, which often appears as a microvascular occlusive disorder (thrombotic microangiopathy, TMA). We report the first case of a microvascular occlusive d...

One year after kidney transplantation, a 70-year-old man returned to haemodialysis. Induction had consisted in basiliximab, mycophenolate, prednisone and cyclosporine, the latter was switched to tacrolimus after 9 months. Because of rejection under reduced immunosuppression, the graft was removed 6 months after returning to haemodialysis and immunosuppression was completely stopped. Twelve mont...