In this paper we present a time-gated single-photon avalanche diode (SPAD) array, the first of its kind to be integrated with a newly developed time-resolved laser Raman spectrometer. Time-resolved Raman spectra from various highly fluorescent minerals were successfully observed using our SPAD array; these spectra were obscured by an overwhelming fluorescence background when measured using a tr...

A retrospective evaluation of attitudinal, behavioural and knowledge change among diverse stakeholder groups was conducted in Limpopo Province of South Africa to assess the effectiveness of a series of values clarification (VC) interventions. Telephone and face-to-face interview (193) results revealed that over two-thirds (70.2%) reported behavioural changes and 93.2% reported increased compass...

We have successfully demonstrated video-rate CMOS single-photon avalanche diode (SPAD)-based cameras for fluorescence lifetime imaging microscopy (FLIM) by applying innovative FLIM algorithms. We also review and compare several time-domain techniques and solid-state FLIM systems, and adapt the proposed algorithms for massive CMOS SPAD-based arrays and hardware implementations. The theoretical e...

We incorporate newly developed solid-state detector technology into time-resolved laser Raman spectroscopy, demonstrating the ability to distinguish spectra from Raman and fluorescence processes. As a proof of concept, we show fluorescence rejection on highly fluorescent mineral samples willemite and spodumene using a 128×128 single-photon avalanche diode (SPAD) array with a measured photon det...

BACKGROUND After resection of long-segment Hirschsprung's disease, severe perianal dermatitis (SPAD) may occur because of high stool frequency and elevated concentrations of fecal pancreatic proteases. We investigated prospectively the effect of potato-derived protease inhibitors (PPI) on skin conditions in children with postoperative SPAD. METHODS Four children (aged 12 to 24 months) with th...

A highly accurate method for the determination of the detection efficiency of a silicon single-photon avalanche diode (Si-SPAD) is presented. This method is based on the comparison of the detected count rate of the Si-SPAD compared to the photon rate determined from a calibrated silicon diode using a modified attenuator technique, in which the total attenuation is measured in two attenuation st...

monly used instruments is a Minolta SPAD (soil plant analysis development) meter. The SPAD meter measures the difference in light absorption at 430 and 750 nm (Wood et al., 1992). The former is the transmittance peak for chlorophyl ‘a’ and ‘b’, and the latter is in the near-infrared region. The instrument converts the difference in light absorption at these two wavelengths into a numerical SPAD...

The appearance of miniaturized single-photon detectors has enabled massively parallel conversion of photons to digital signals that can be readily processed and/or transported with negligible losses. As a consequence, a new class of imaging sensors is emerging, known collectively as all-digital image sensors, for detection and processing of ultra-fast and complex photonic events, often present ...

Vegetation phenology, as used and studied the related studies, refers to the relationship between climate and periodic development of photosynthetic biomass. selected 15 Hornbeam plots (Carpinus betulus) from study area in a mountainous region from 520m to 1310m above sea level. Ground observations of hornbeam tree growth process from January to December 2004 in 15 day intervals were performed ...