نتایج جستجو برای: soluble p
تعداد نتایج: 1347082 فیلتر نتایج به سال:
BACKGROUND P-selectin, a cell-surface adhesion molecule involved in leukocyte rolling and attachment, has been hypothesized to play a role in the initiation of atherosclerosis. However, little clinical data are available evaluating the role of soluble P-selectin in determining vascular risk. METHODS AND RESULTS In a large-scale prospective study of apparently healthy women, we measured baseli...
in line with an investigation regarding to evaluation of the compatibility of the asian pear cultivars with iran climatic conditions – currently being carried out at the horticultural department of tarbiyat modares university (tmu) – the present preliminary study was performed in two regions in isfahan. asian pear (pyrus serotina rehd.) cultivars (grafted on european pear seedling rootstocks) w...
BACKGROUND Hypercholesterolemia is considered a major risk factor for the development of atherosclerosis. Enhanced lipid peroxidation and persistent platelet activation can be observed in vivo in hypercholesterolemic patients and may have pathophysiological implications in the occurrence of cardiovascular events. P-selectin may play an important role in the pathogenesis of multicellular events,...
Measurement of soluble (s) P-selectin levels has been proposed as a diagnostic tool for monitoring the clinical course of human neoplasms. Thus, our study was aimed at analyzing the role of sP-selectin in association with clinicopathological variables in 181 patients with primary (n =149) or metastatic (n = 32) colorectal cancer (CRC), 34 patients with benign diseases and 181 control subjects. ...
intermediary drives ibrutinib resistance, whereas presence of a complex karyotype and Del17p are predictive of progression while on ibrutinib. Additional work in larger cohorts of samples may be required to address whether USP7 inhibition would be sufficient to target disease in this subgroup of patients. In conclusion, despite unresolved queries, this study identifies that USP7 is an attractiv...
Soluble P-selectin (sP-selectin), a biomarker of inflammatory related pathologies including cardiovascular and peripheral vascular diseases, also has pro-atherosclerotic effects including the ability to increase leukocyte recruitment and modulate thrombotic responses in vivo. The current study explores its role in progressing atherosclerotic plaque disease. Apoe-/- mice placed on a high fat die...
Increasing the altitude causes extensive changes in the environmental conditions. Three species of Quercus brantii Lindl., Pistacia atlantica Desf. and Crataegus pontica C. Koch. are the dominant species in the forests of Ilam province. The sampling was done from Qalajeh Mountain at the altitude from 1300-2000 m a.s.l. The effect of altitude on photosynthesis, photosynthetic pigments and some b...
INTRODUCTION AND OBJECTIVES Neprilysin breaks down numerous vasoactive peptides. The soluble form of neprilysin, which was recently identified in heart failure, is associated with cardiovascular outcomes. Within a multibiomarker strategy, we directly compared soluble neprilysin and N-terminal pro-B-type natriuretic peptide as risk stratifiers in a real-life cohort of heart failure patients. M...
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