Abstract Arsenic trioxide (ATO) is a promising chemotherapeutic agent, but its clinical application limited due to poor pharmacokinetics and dose-limited toxicity. Moreover, the combination of ATO sec-o-glucosylhamaudol (SOG) can improve therapeutic effect hepatoma. In this study, PEGylated magnetic nanographene oxide (PEG@MGO) was used as carriers enhance targeting ability drug delivery system...

The developing crossveins of the wing of Drosophila melanogaster are specified by long-range BMP signaling and are especially sensitive to loss of extracellular modulators of BMP signaling such as the Chordin homolog Short gastrulation (Sog). However, the role of the extracellular matrix in BMP signaling and Sog activity in the crossveins has been poorly explored. Using a genetic mosaic screen ...

Vehicle speed-over-ground (SoG) radar offers significant advantages over conventional speed measurement systems. Radar sensors enable contactless speed measurement, which is free from wheel slip. One of the key issues in SoG radar is the development of the Doppler shift estimation algorithm. In this paper, we compared two algorithms to estimate a mean Doppler frequency accurately. The first is ...

Previous studies have shown that taking into account another person's perspective to guide decisions is more difficult when their perspective is incongruent from one's own compared to when it is congruent. Here we used dynamic causal modelling (DCM) for functional magnetic resonance imaging (fMRI) to investigate effective connectivity between prefrontal and posterior brain regions in a task tha...

Etoricoxib features antioxidant and anti-inflammatory properties concomitantly, suggesting that it may be beneficial in testicular ischemia reperfusion (I/R) damage. Our aim is to investigate the effects of etoricoxib on testicular I/R damage induced with torsion-detorsion (TD). The etoricoxib + torsion-detorsion (ETD) groups of animals were given etoricoxib in 50 and 100 mg/kg of body weight (...

Extracellular inhibitors are commonly used in development to modulate the activities of signalling molecules. Direct visualisation in the Drosophila embryo of Sog, a Dpp/Scw inhibitor, has now revealed a graded distribution established by degradation and endocytosis.

In this work, the effects of frequency dependence transparent dielectric based on Spin-on Glass (SOG) under electrical stress is presented. The SOG thin films were cured at 200 °C in ambient air. capacitance-voltage and capacitance-frequency characteristics measured Metal-Oxide-Semiconductor (MOS) capacitors using film. addition, applied to MOS different voltage values during a long period time...

BACKGROUND Sleeve gastrectomy (SG) has emerged recently as a stand-alone bariatric procedure to treat morbid obesity and enhance glucose homeostasis. The aim of the study was to evaluate its effects in neonatally streptozotocin (STZ)-induced diabetic rats (n-STZ diabetic rats). METHODOLOGY AND PRINCIPAL FINDINGS To induce diabetes, STZ (90 mg/kg) was administered intraperitoneally to 2-day-ol...