Clinical studies have shown that in pathological conditions such as endometriosis and reproductive tract infection (male and female) there is an activation status of macrophages that produce large quantities of nitric oxide (NO) in addition to other effector molecules. Large amounts of NO may have embryotoxic roles and produce infertility. This study was designed to evaluate the effect of diffe...

Thirty patients who developed arterial hypertension following coronary artery bypass grafting, despite sedation, were treated randomly with sodium nitroprusside (SNP), ketanserin or urapidil. All drugs significantly decreased arterial pressure. Two patients were withdrawn because hypertension failed to respond to ketanserin. Significant tachycardia was noted only in the SNP group. An increase i...

Cadmium (Cd) causes oxidative stress, which leads to the oxidation of various biomolecules by production reactive oxygen species (ROS) facilitate programmed cell death (PCD). The antioxidant defense system fails detoxify ROS when it is produced in excess. Nitric oxide (NO), a gaseous free radical and phytohormone, regulates physiological processes plants. Therefore, this work was undertaken stu...

The effect of nitric oxide (NO) on the luminol-dependent chemiluminescence (LCL) response of rat polymorphonuclear leukocytes (PMNLs) was analyzed by using sodium nitroprusside (SNP), a NO donor, and L-arginine (L-arg), a NO precursor. A significant reduction in the LCL intensity was observed in presence of SNP (100 pmol/L) or L-arg (5 or 10 mmol/L) in arachidonic acid (AA) phorbol ester (PMA) ...

Cerebral blood flow and metabolism have been studied in 11 patients during general anaesthesia and hypotension induced with sodium nitroprusside in combination with captopril. Cerebral blood flow was measured, using a Novo Cerebrograph model 10A, after injection of 133 xenon into an arm vein. Arterial and venous blood samples were drawn to calculate cerebral metabolism. Captopril 1 mg.kg-1 oral...

clinical studies have shown that in pathological conditions such as endometriosis and reproductive tract infection (male and female) there is an activation status of macrophages that produce large quantities of nitric oxide (no) in addition to other effector molecules. large amounts of no may have embryotoxic roles and produce infertility. this study was designed to evaluate the effect of diffe...

As a bioactive signal, nitric oxide (NO) is involved in multiple plant physiological responses, especially under some abiotic stress. Here, we investigated the effects of exogenous nitric oxide on both the reactive oxygen species (ROS) scavenging metabolism and regulating functions of plasma membrane and tonoplast in tomato plants treated with 50μM CuCl2. Copper stress induced significant accum...

Twenty-six patients, receiving an infusion of sodium nitroprusside (SNP) during surgery, had considerable increases in both red cell and plasma cyanide concentration, but only small changes in plasma thiocyanate concentration. There was a linear relationship between both plasma and RBC cyanide concentrations and the total dose of SNP. The expired cyanide concentration followed the changes in th...

The conversion of nitric oxide (NO*) into its congeners nitrosonium (NO(+)) and nitroxyl (HNO/NO(-)) ions may have important consequences for signal transduction and physiological responses. Manganese-containing superoxide dismutase (MnSOD) may convert NO. into its redox congeners. In our current work, we have examined the mechanism of sodium nitroprusside (SNP)-induced relaxation of arteries, ...