The useful imaging range in spectral domain optical coherence tomography (SD-OCT) is often limited by the depth dependent sensitivity fall-off. Processing SD-OCT data with the non-uniform fast Fourier transform (NFFT) can improve the sensitivity fall-off at maximum depth by greater than 5dB concurrently with a 30 fold decrease in processing time compared to the fast Fourier transform with cubic...

M2BP (also called 90K) is an interferon-stimulated gene product that is upregulated in HIV-1 infection. A recent study revealed that M2BP reduces the infectivity of HIV-1 by inhibiting the processing of the viral envelope protein. Here we report that in addition to reducing viral infectivity, M2BP inhibits HIV-1 virion production. We provide evidence showing that M2BP inhibits HIV-1 Gag traffic...

SPAIDE (sound-processing algorithm integrated development environment) is a real-time platform of Advanced Bionics Corporation (Sylmar, Calif, USA) to facilitate advanced research on sound-processing and electrical-stimulation strategies with the Clarion CII and 90K implants. The platform is meant for testing in the laboratory. SPAIDE is conceptually based on a clear separation of the sound-pro...

Galectins, a family of structurally related carbohydrate-binding proteins, contribute to different events associated with cancer biology, including apoptosis, homotypic cell aggregation, angiogenesis and tumor-immune escape. To interfere with galectin-carbohydrate interactions during tumor progression, a current challenge is the design of specific galectin inhibitors for therapeutic purposes. H...

An advanced recombination model based on the Shockley-Read-Hall-statistics with full trap dynamics is used for the simulation of irradiated power diodes. The model makes use of the rate equations which also take into account the dynamic effects in the space charge region of the power devices. The high-level lifetime calculated from DLTS (Deep Level Transient Spectroscopy) data does not agree we...

We present an approach, called the Shadow Method, for the identification of disease loci from dense genetic marker maps in complex, potentially incomplete pedigrees. Shadow is a simple method based on an analysis of the patterns of obligate meiotic recombination events in genotypic data. This method can be applied to any high density marker map and was specifically designed to exploit the fact ...

A computing policy is a sequence of rules, where each rule consists of a predicate and a decision, and where each decision is either “accept” or “reject”. A policy P is said to accept (or reject, respectively) a request iif the decision of the first rule in P , that matches the request is “accept” (or “reject”, respectively). Examples of computing policies are firewalls, routing policies and so...

A light-beam-assisted temperature-control system operating within a temperature range from 77 to 180 K is developed for investigating the absorption of electromagnetic waves by high-temperature superconductors in the vicinity of superconducting transition with an ESR spectrometer. The advantage of this system is the feasibility of modulating the temperature of a sample with a frequency of 80 Hz...