Previous reports have indicated the usefulness of Io per cent. Guanethidine eye-drops in reducing lid retraction and relieving symptoms in patients with dysthyroid eye disease (Sneddon and Turner, I966; Gay and Wolksteip, I966; Crombie and Lawson, I967). Administration of these eye drops produces local irritation in about 50 per cent. of patients and, although this is rarely severe, superficial...