نتایج جستجو برای: skin permeability rate

تعداد نتایج: 1179169  

2011
Bijaya Ghosh Naresh Rajgor Jayesh Patel

Delivering medicine to the general circulation through the skin is associated with grater advantages compared to that by the oral route and hence the purpose of this investigation was to study the potential of rosiglitazone maleate for transdermal delivery using passive diffusion and iontophoresis. Physicochemical parameters of rosiglitazone maleate like solubility, pKa, octanol/vehicle and ski...

Journal: :Infection and immunity 1980
J E Rehg

The cecal contents of guinea pigs with clindamycin-associated colitis contained a heat-labile toxin. This toxin was lethal for guinea pigs and mice, produced vascular permeability in the skin of rabbits, and was cytotoxic in tissue culture. The lethality in mice, vascular permeability in rabbit skin, and cytotoxicity in tissue culture monolayers were neutralized by Clostridium sordellii antitoxin.

2011
Jessica Stahl Michael Braun Joerg Siebert Manfred Kietzmann

BACKGROUND A water based combination of 0.1% octenidine dihydrochloride and 2% 2 - phenoxyethanol is registered in many European countries as an antiseptic solution (octenisept®) for topical treatment with high antimicrobial activity for human use, but octenidine based products have not been registered for veterinary use yet. The aim of the present study was to investigate whether octenidine di...

ژورنال: پوست و زیبایی 2012
رجبی استرآبادی, علی, زرتاب, حامد, فیروز, علیرضا,

Skin is the largest organ of the integumentary system with multiples important functions. Due to its complex structure, the permeability skin status can be modified by different external and internal factors such as chemical and physical stresses, and several skin and systemic diseases. Today, different non-invasive methods are used to assess the skin barrier biophysical properties. The paramet...

Journal: :Skin pharmacology and physiology 2010
J Liu W Y Man C Z Lv S P Song Y J Shi P M Elias M Q Man

BACKGROUND/OBJECTIVES Prior studies have demonstrated that both the skin surface pH and epidermal permeability barrier function vary with skin pigmentation types. Although melanin deficiency is the main feature of vitiligo, alterations in cutaneous biophysical properties in vitiligo have not yet been well defined. In the present study, stratum corneum (SC) hydration, the skin surface pH and epi...

Journal: :The Yale Journal of Biology and Medicine 1981
S. M. Fortney V. A. Koivisto P. Felig E. R. Nadel

Because diabetics are prone to the development of neuropathy and microvascular disease, abnormalities of cardiovascular reactivity and capillary permeability in response to acute exercise and/or an increase in environmental temperature might presage the development of clinically overt complications. In the present study insulin-dependent diabetics without evidence of microangiopathy or neuropat...

Journal: :Archives of disease in childhood 1994
D A Barrett N Rutter

The permeability of the skin of newborn infants to lignocaine was examined in vitro using excised skin. Samples were studied from 24 infants of gestational age 25 to 40 weeks and postnatal age 0 to 7 days. Mature skin was relatively impermeable to lignocaine, but the more premature infants showed a marked increase in absorption. There was a strong inverse correlation between gestational age and...

2011
Satya Sagar Saxena G. K. Dubey

An analysis has been carried out to obtain the free convective heat and mass transfer characteristics of an incompressible MHD viscoelastic fluid flow immersed in a porous medium of variable permeability bounded by an infinite porous vertical plate in slip flow regime in the presence of a transverse magnetic field with heat source and radiation effects. The permeability of the porous medium dec...

2014
M. Muthtamilselvan D. Prakash

The effect of non-uniform heat generation on an unsteady MHD laminar boundary layer flow of viscous, incompressible fluid over a vertical stretching plate embedded in a sparsely packed porous medium is investigated numerically. The flow in the porous medium is governed by Brinkman-Forchheimer extended Darcy model. The variation of porosity, permeability and thermal conductivity is assumed. By a...

Journal: :International Journal of Pharmaceutics 2011

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