A 42-year-old asplenic woman was evaluated for a 2-week history of intermittent high-grade fevers and pleuritic chest pain and skin rash (figure 1). A CTscan of the chest showed multiple small nodules on both lungs (figure 2). Fungal serological studies were negative. A skin biopsy revealed palisading dermal granulomatous inflammation with focal vascular destruction and was negative for any org...

Nodular tuberculid (NT) was originally described by Jordaan et al. in 2000 in 4 patients from South Africa. It appeared as nodules on the legs; the pathologic changes were situated in the deep dermis and adjacent subcutaneous fat. A 34-year-old woman visited our hospital with subcutaneous skin-colored or slightly erythematous round to oval nodules. Skin biopsies revealed granulomatous inflammat...

BACKGROUND Keratoacanthomas usually occur spontaneously as a single rapidly growing tumor on sun-exposed skin. Multiple keratoacanthomas are rarely seen. Keratoacanthomas may also develop after trauma, laser resurfacing, radiation therapy, and at the donor site after skin grafting. OBJECTIVE We report 6 cases of keratoacanthomas that developed in and around healing and healed surgical sites a...

Knuckle pads is a syndrome characterized by the presence of multiple nodules located on the extensor side of the interphalangeal or metacarpophalangeal joints. Several conditions can be confused with Knuckle pads. We describe a case of a 47-years-old man who developed multiple bilateral roundish nodules located in the skin over the dorsal and lateral interphalangeal joints in both hands.

Lymphomatoid granulomatosis is an uncommon disorder that can present as multiple pulmonary nodules. Systemic manifestations such as fever, weight loss, skin lesions, and other organ involvement may occur. The clinical presentation of lymphomatoid granulomatosis can mimic infectious diseases (eg, tuberculosis), vasculitis, or metastatic malignancies.1 Lymphomatoid granulomatosis should be consid...

A 69-year-old male with granulomatosis with polyangiitis presented with new skin nodules. Skin biopsy showed metastatic poorly differentiated lung adenocarcinoma. The skin nodule was the initial presentation of his lung cancer. There is need for increased vigilance for cancer risk in ANCA-associated vasculitis patients.

We presents an infant with several indurated plaques and nodules scattered on her body. She was brought to the hospital because of fever, runny nose and cough from one month ago. During the examination and investigation the plaques and nodules grabbed the attention of the clinicians and the skin biopsy and other lab works revealed the diagnosis of congenital leukemia.

Precalcaneal congenital fibrolipomatous hamartomas (PCFHs) are characterized clinically by the presence of unilateral or bilateral, asymptomatic nodules in the medial precalcaneal plantar region of the heel. They are skin colored and usually painless nodules. In most patients, the lesions appear within the first few months of life, but they may also be present at birth. Generally PCFHs are beni...

Leukocytoclastic vasculitis (LCV), also termed hypersensitivity vasculitis, is a small-vessel vasculitis. The skin is the organ most commonly involved in LCV. Typical presentation is a painful, burning rash predominantly in the lower extremities. The most common skin manifestation is palpable purpura. Other skin manifestations include maculopapular rash, bullae, papules, plaques, nodules, ulcer...

In this case report, we will describe a gastric cancer case, which presented with rare manifestation of skin metastases and unrelated to the mechanical impact distant scleroderma-like paraneoplastic rheumatic syndrome.
 72-year-old woman was referred hospital complaints gradual during time period one year. Skin changes included - thickening, dermal induration mostly seen on her upper body ...