Initially, the eruptions started as papules, which evolved into pustules and then crusted lesions. There was no history of fever, arthralgia or abdominal pain. The patient had not taken any medications for any other illness for at least 3 months before the onset of these skin eruptions. He had not suffered from any major medical or surgical illness in the past. There was no history of similar e...

The levels of immune complex-like material in serum from 18 patients in connection with skin eruptions appearing during penicillin therapy were determined with a modified ELISA. Immune complex-like material could only be shown in the serum of 3 out of the 17 patients. However, according to ELISA results, the complexes appeared without the simultaneous presence of penicilloyl-specific antibodies...

A 38-year-old male suffering from a low backache since 3 months was diagnosed as a case of L4-L5 disc prolapse after magnetic resonance imaging examination. He was treated with tolperisone, aceclofenac, and paracetamol in these drugs deflazacort added later. From the 2nd day of an addition of deflazacort in the therapy, sharply marginated, infiltrative, and erythematous skin eruptions with disc...

Chronic active Epstein-Barr virus (EBV) disease (CAEBV) is a systemic EBV-positive lymphoproliferative disorder characterized by fever, lymphadenopathy, and splenomegaly. Patients with CAEBV may present with cutaneous symptoms, including hypersensitivity to mosquito bites and hydroa vacciniforme (HV)-like eruptions. HV is a rare photodermatosis characterized by vesicles and crust formation afte...

Adult T-cell lymphoma (ATL) was first reported by Uchiyama et al. (1) as a distinct malignancy of mature T cells occurring primarily in patients born in southwestern Japan (2). Patients with epidermodysplasia verruciformis (EV) present in childhood with numerous thin, pink, flat papules and plaques that resemble verruca plana (3). EV is mainly caused by the human papilloma virus (HPV) types 5 a...

Cutaneous infections due to Listeria monocytogenes are rare. Typically, infections manifest as nonpainful, nonpruritic, self-limited, localized, papulopustular or vesiculopustular eruptions in healthy persons. Most cases follow direct inoculation of the skin in veterinarians or farmers who have exposure to animal products of conception. Less commonly, skin lesions may arise from hematogenous di...

Erlotinib is low molecular-weight quinazolin derivatives which selectively inhibit the epidermal growth factor receptor (EGF-R) tyrosine kinase activity of the intracellular domain, block autophosphorylation and the subsequent signaling cascades. EGF-R is expressed on basal keratinocytes, sebocytes, the outer root sheath of hairs, and endothelial cells in the skin, and plays important roles in ...

Sebotropic mites have been implicated in the pathogenesis of several dermatoses in humans. A 46 year old male diabetic patient presented with painful, erythematous, papular, rosacea-like eruptions over bilateral cheeks and a rhinophyma of the nasal tip. The lesions were persistent for two years, with negative slit skin smears and unresponsive to treatment attempts. A skin biopsy revealed demode...