In humans, structural and functional changes attributable to aging are more visibly evident in the skin than in any other organ. Estrogens have significant effects on skin physiology and modulate epidermal keratinocytes, dermal fibroblasts and melanocytes, in addition to skin appendages including the hair follicle and the sebaceous gland. Importantly, skin aging can be significantly delayed by ...

Hair follicles play an important role in hair development. This study aimed to develop a microgel-spotting device fabricate multilayered gel bead culture model and mimic the early development of skin appendages regenerate vitro. The consists alginate layer containing cytokines as core layer, collagen mouse embryonic stem cells middle fetus-derived epidermal outer layer. A concentration gradient...

Augmenting human appearance with the means of technology can focus on different layers attached to or around body. In this article, we present a categorization and expression, augmenting skin its appendages, clothing textile, accessories, body parts, digital aura We report non-systematic review related works in each category discuss their expressing functional, hedonic, social aspects. conclusi...

Abstract: Photothermal radiometry is an infrared remote sensing technique that has been used for skin and skin appendages research, in the areas of skin hydration, hydration gradient, skin hydration depth profiling, skin thickness measurements, skin pigmentation measurements, effect of topically applied substances, transdermal drug delivery, moisture content of bio-materials, membrane permeatio...

The human skin vasculature has distinct anatomy with two vascular plexuses and specialized capillary loops near appendages rete ridges, diverse functions including thermal regulation immune cell trafficking. There is currently no engineered 3D model to capture this level of complexity. goal study generate an anatomically-relevant five different types, patterned hair follicles, a perfusable micr...

The epidermis is a derivative of the surface ectoderm. It forms a protective barrier and specific appendages including hair, nails, and different eccrine glands. The surface ectoderm also forms the epithelium of the oral cavity and tongue, which develop a slightly different barrier and form different appendages such as teeth, filiform papillae, taste papillae, and salivary glands. How this regi...

Cutaneous squamous cell carcinoma is a malignant tumour of the keratinising cells epidermis or its appendages. It constitutes 20% skin malignancy. UV radiation exposure most common cause cancer with sun exposed face and upper trunk being site for occurrence. Long term to chemical carcinogen, burn scar, chronic ulcer among other risk factors. Skin biopsy mainstay diagnosis in suspected lesion SC...

The skin offers an ideally suited, clinically relevant model for studying the crossroads between peripheral and systemic responses to stress. A 'brain-skin connection' with local neuroimmunoendocrine circuitry underlies the pathogenesis of allergic and inflammatory skin diseases, triggered or aggravated by stress. In stressed mice, corticotropin-releasing hormone, nerve growth factor, neurotens...

Sulphur Mustard is a potent chemical warfare agent that was widely used during first world war and Iran ‌Iraq conflict. Over 100,000 Iranians were injured by sulphur mustard and one-third is of them were suffering from late effects until today. This vesicant agent has a lot of acute and chronic destructive effects on the skin, eye and respiratory system. Sulphur mustard via the alkylations of s...