نتایج جستجو برای: skin aging

تعداد نتایج: 293423  

2014
Elodie Metral Morgan Dos Santos Amélie Thépot Walid Rachidi Ali Mojallal Odile Damour

Objectives: Skin aging is subject of many studies in esthetic surgery including several morphological changes like decrease of epidermis thickness and of cell proliferative potential. ASC, mesenchymal stem cells derived from adipose tissue, have been used in regenerative and reparative surgery as well as anti-aging solution. The aim of this study was to highlight the influence of ASCs on skin a...

Journal: :Dermato-Endocrinology 2012

Journal: :Sen'i Gakkaishi 1998

Journal: :Journal of Investigative Dermatology 2017

2013
Anne Lynn S Chang Patrick H Bitter Kun Qu Meihong Lin Nicole A Rapicavoli Howard Y Chang

Studies in model organisms suggest that aged cells can be functionally rejuvenated, but whether this concept applies to human skin is unclear. Here we apply 3'-end sequencing for expression quantification ("3-seq") to discover the gene expression program associated with human photoaging and intrinsic skin aging (collectively termed "skin aging"), and the impact of broadband light (BBL) treatmen...

Journal: :The Journal of investigative dermatology 2017
Matthew H Law Sarah E Medland Gu Zhu Seyhan Yazar Ana Viñuela Leanne Wallace Sri Niranjan Shekar David L Duffy Veronique Bataille Dan Glass Tim D Spector Diane Wood Scott D Gordon Julie M Barbour Anjali K Henders Alex W Hewitt Grant W Montgomery Richard A Sturm David A Mackey Adèle C Green Nicholas G Martin Stuart MacGregor

Loss of fine skin patterning is a sign of both aging and photoaging. Studies investigating the genetic contribution to skin patterning offer an opportunity to better understand a trait that influences both physical appearance and risk of keratinocyte skin cancer. We undertook a meta-analysis of genome-wide association studies of a measure of skin pattern (microtopography score) damage in 1,671 ...

2013
Rajashree Hirlekar Varsha Patil

Skin aging is influenced by many factors including ultraviolet radiation, excess alcohol consumption, tobacco abuse, and environmental pollution. Age-related skin changes are the result of genetically programmed changes (intrinsic factors) and environmental wear-and-tear on the skin (extrinsic factors). This article also provides information about wrinkles development and the approaches to stim...

2012
Nicolai Treiber Pallab Maity Karmveer Singh Florentina Ferchiu Meinhard Wlaschek Karin Scharffetter-Kochanek

The free radical theory of aging postulates that the production of mitochondrial reactive oxygen species is the major determinant of aging and lifespan. The skin represents an excellent and accessible model organ to study aging that is characterized by atrophy, wrinkle formation, reduced tensile strength and impaired wound healing. Oxidative stress as a consequence of an imbalance in prooxidant...

Journal: :Clinical pharmacology and therapeutics 2011
D L Sachs J J Voorhees

The quest for youth and beauty is an ongoing one. No organ conveys youth and beauty to the extent that skin does. Advances in research over the past several decades have yielded a tremendous amount of information on the molecular pathways involved in both intrinsic aging (natural) and extrinsic aging (photoaging). In this article, we aim to describe the molecular pathways that lead to an aged a...

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