Various types of motion and deformation the lung undergoes during minimally invasive tumor ablative procedures, e.g. Low Dose Rate (LDR) brachytherapy, have been investigated and modeled in this dissertation. Modeling such motions and deformations are highly necessary for enhancing the accuracy of lung’s Minimally Invasive Surgery (MIS). This necessity stems from the fact that due to its porous...

The use of biomarkers to refine patient populations, such that clinical trials will be most likely to provide a definitive answer requiring the fewest patients, is particularly appealing for application to research involving patients with a heterogeneous syndrome like ALI/ARDS. This could be beneficial by helping to characterize either a group of patients with a high mortality where mortality i...

BACKGROUND The incidence of acute lung injury (ALI) in hypoxic patients undergoing surgery is currently unknown. Previous studies have identified lung protective ventilation strategies that are beneficial in the treatment of ALI. The authors sought to determine the incidence and examine the use of lung protective ventilation strategies in patients receiving anesthetics with a known history of A...

RATIONALE Accurate, early identification of patients at risk for developing acute lung injury (ALI) provides the opportunity to test and implement secondary prevention strategies. OBJECTIVES To determine the frequency and outcome of ALI development in patients at risk and validate a lung injury prediction score (LIPS). METHODS In this prospective multicenter observational cohort study, pred...

the 7th international congress of child and adolescent psychiatry 12-14 may 2015, tehran, iran shahid beheshti university of medical sciences, tehran conference theme: violence prevention and promotion of mental health head of congress: mehdi tehrani-doost, m.d scientific secretary: rozita davari ashtiani, m.d executive secretary: katayoun razjouyan, m.d executive manager: fahima farrahi the sc...

Para analisar um certo percurso da obra de Said Ali, decisivo na história das ideias linguísticas no Brasil, tomo dois acontecimentos. De lado a publicação Gramática Secundária (uma gramática normativa, que ele chama prática) e Estrutura Língua Portuguesa Mattoso Câmara, em 1970. Com esta análise procuramos refletir sobre questão do purismo, lado, consideração uma norma linguística outro. Podem...

OBJECTIVE This study aimed to investigate the expression and role of Nrf2 in the acute lung injury (ALI) of mice. METHODS A total of 60 BABL/c mice were randomly divided into 2 groups: ALI group and control group. In ALI group, ALI was introduced by injection of LPS. Immunohistochemistry was performed to detect Nrf2 expression in the lung; Western blot assay was employed to detect the express...

Study objectives: To assess the gas exchange and hemodynamic effects of pressure-limited ventilation (PLV) strategies in acute lung injury (ALI). We hy¬ pothesized that in ALI, the reduction ofplateau airway pressure (Paw) would be associated with less alveolar overdistention and thus have better hemodynamic and gas exchange characteristics than larger tidal volume (Vt) ventilation. Setting: La...

BACKGROUND AND PURPOSE Acute lung injury (ALI) remains a major challenge in critical care medicine. Both neutrophils and chemokines have been proposed as key components in the development of ALI. The main chemokine receptor on neutrophils is CXCR2, which regulates neutrophil recruitment and vascular permeability, but no small molecule CXCR2 inhibitor has been demonstrated to be effective in ALI...