Renal cystic diseases encompass a broad group of disorders with variable phenotypic expression. Cystic disorders can present during infancy, childhood, or adulthood. Often, but not always, they can be distinguished by the clinical features including age at presentation, renal imaging characteristics, including cyst distribution, and the presence/distribution of extrarenal manifestations. It is ...

www.aafp.org/afp VOLUME 63, NUMBER 2 / JANUARY 15, 2001 these lesions are benign simple cysts that require no further evaluation, intervention or urologic consultation. The primary reason to investigate a renal mass is to exclude a malignant neoplasm. One screening study using ultrasound examinations found clinically or pathologically malignant renal tumors in 12 (0.2 percent) of 5,898 consecut...

A subset of familial and sporadic clear cell renal cell carcinomas (ccRCCs) is believed to develop from cystic precursor lesions. Loss of function of the von Hippel-Lindau tumor suppressor gene (VHL) predisposes renal epithelial cells to loss of the primary cilium in response to specific signals. Because the primary cilium suppresses renal cyst formation, loss of the cilium may be an initiating...

PURPOSE To carry out long-term follow-up of patients diagnosed with asymptomatic simple renal cysts (SRCs). MATERIALS AND METHODS One hundred fifty-eight adult patients in whom SRCs were incidentally diagnosed by abdominal ultrasonography or abdominopelvic computed tomography between August 1994 and June 2004 were followed up for over 10 years. The retrospective analysis investigated sequenti...

The renal tubules, in their various segments, are mainly responsible for the final composition of urine from glo­ merular ultrafiltrate. In a complex process involving resorption and secretion mechanisms, the tubules are responsible for retaining substances in the body, some substances are recovered almost 100% such as water and sodium chloride. Tubulopathies are a group of diseases where these...

BACKGROUND Thoracic aortic aneurysm is usually a clinically silent disease; timely detection is largely dependent upon identification of clinical markers of thoracic aortic disease (TAD); (bicuspid aortic valve, intracranial aortic aneurysm, bovine aortic arch, or positive family history). Recently, an association of simple renal cysts (SRC) with abdominal aortic aneurysm and aortic dissection ...

Renal cysts are common and most often are discovered incidentally, but may require intervention if associated with pain, hypertension, or hematuria. Minimally invasive treatment options are preferred with numerous modalities available, including renal cyst ablation. This case report of a 61-year-old female describes the effective percutaneous drainage and endoscopic ablation of a simple parapel...