Chronic wounds represent a large and growing segment of health care and add considerably to human suffering and economic burden as populations age. More effective materials, especially those promoting ease of use and economy, are needed to treat this increasing number of patients. A case series conducted at a European outpatient tertiary wound centre used a novel surfactant-based biomaterial dr...

Burn wound infection delays wound healing, leading to varying degrees of morbidity and mortality. Various antibiotics are administered to burn patients in burn wound management. The emergence of antibiotic resistance is a menace that costs families and the country. This review seeks to expound on infections related to burn wounds, common bacteria of burn wound infections and choice of antibioti...

Burn injury is associated with a high incidence of death and disability; yet, its management remains problematic and costly. We conducted this clinical study to evaluate the efficacy of honey in the treatment of superficial and partial-thickness burns covering less than 40% of body surface area and compared its results with those of silver sulphadiazine (SSD). In this randomised comparative cli...

The usefulness of sulphaguanidine in the treatment of cholera, especially in its early stage, was discussed in a previous paper published by the author (1945). The absorbable sulphonamides however do not appear to have been as yet much tried for the treatment of this disease. Hardy et al. (1943) and Hardy and Cummins (1943) published two papers indicating very good curative action of sulphadiaz...

A 3-year-old girl is described who became oliguric and hypoglycaemic whilst receiving an excessive dose of sulphadiazine. The mechanism of the hypoglycaemia is discussed.

OBJECTIVE Ivermectin and sulphadiazine were tested individually to determine their in vitro effects on Toxoplasma gondii grown in human epidermoid larynx carcinoma (Hep-2) cell culture. STUDY DESIGN In-vitro study. MATERIAL AND METHODS Toxoplasma growth was quantities by an enzyme immunoassay performed directly on the fixed cultures, using a rabbit anti-T. gondii immunoglobulin G as the fir...

Sulphadiazine, [4-amino-N-(2-pyrimidinyl)-benzenesulfonamide], reacts with (dppe)Au2Cl2 and triethylamine in methanol to produce [(SDAZ)2Au2(dppe)]. The structure of this novel complex was analyzed by single crystal X-ray diffraction. In [(SDAZ)2Au2(dppe)] the ligands SDAZ− and dppe have approximately the same bond distances and angles as found for the protonated and free ligand, respectively. ...

OBJECTIVE To investigate topical honey in superficial burns and wounds though a systematic review of randomised controlled trials. DATA SOURCES Cochrane Library, MEDLINE, EMBASE, PubMed, reference lists and databases were used to seek randomised controlled trials. Seven randomised trials involved superficial burns, partial thickness burns, moderate to severe burns that included full thickness...