نتایج جستجو برای: signatures of selection

تعداد نتایج: 21196251  

2013
David Enard Philipp W. Messer Dmitri Petrov

The role of positive selection in human evolution remains highly controversial (Cai et al. positive selection have identified hundreds of candidate loci and the genome-wide patterns of polymorphism show signatures consistent with frequent positive selection. On the other hand, recent studies have argued that many of the candidate loci are false positives and that most apparent genome-wide signa...

پایان نامه :دانشگاه تربیت معلم - تهران - دانشکده ادبیات و علوم انسانی 1391

the present study aimed at exploring cognitions of iranian english teachers within the context of english for academic purposes (eap). to this end, the cognitions of two groups of eap teachers with respect to their pedagogical content knowledge (pck) and their sense of professional identity (pi) were probed. two language teachers and two content instructors who had at least five years of eap te...

2014
Zhen Wang Qiang Chen Yumei Yang Hongjie Yang Pengfei He Zhe Zhang Zhenliang Chen Rongrong Liao Yingying Tu Xiangzhe Zhang Qishan Wang Yuchun Pan

Pigs have experienced dramatic selection due to domestication, which has led to many different phenotypes when compared to their wild counterparts, especially in the last several decades. Currently, genome-wide scans in both cattle and humans showing positive selection footprints have been investigated. However, few studies have focused on porcine selection footprints, particularly on a genome-...

2013
Samantha Wilkinson Zen H. Lu Hendrik-Jan Megens Alan L. Archibald Chris Haley Ian J. Jackson Martien A. M. Groenen Richard P. M. A. Crooijmans Rob Ogden Pamela Wiener

Following domestication, livestock breeds have experienced intense selection pressures for the development of desirable traits. This has resulted in a large diversity of breeds that display variation in many phenotypic traits, such as coat colour, muscle composition, early maturity, growth rate, body size, reproduction, and behaviour. To better understand the relationship between genomic compos...

پایان نامه :0 1390

انتخاب نامساعد یکی از مشکلات اساسی در صنعت بیمه است. که ابتدا در سال 1960، توسط روتشیلد واستیگلیتز مورد بحث ومطالعه قرار گرفت ازآن موقع تاکنون بسیاری از پژوهشگران مدل های مختلفی را برای تجزیه و تحلیل تقاضا برای صنعت بیمه عمر که تماما ناشی از عدم قطعیت در این صنعت میباشد انجام داده اند .وهدف از آن پیدا کردن شرایطی است که تحت آن شرایط انتخاب یا کنار گذاشتن یک بیمه گزار به نفع و یا زیان شرکت بیمه ...

2015
Xuanshi Liu Kerstin Weidle Kristin Schröck Anke Tönjes Dorit Schleinitz Jana Breitfeld Michael Stumvoll Yvonne Böttcher Torsten Schöneberg Peter Kovacs

BACKGROUND AND AIMS Polymorphisms in the first intron of FTO have been robustly replicated for associations with obesity. In the Sorbs, a Slavic population resident in Germany, the strongest effect on body mass index (BMI) was found for a variant in the third intron of FTO (rs17818902). Since this may indicate population specific effects of FTO variants, we initiated studies testing FTO for sig...

2010
Aida M. Andrés Megan Y. Dennis Warren W. Kretzschmar Jennifer L. Cannons Shih-Queen Lee-Lin Belen Hurle Pamela L. Schwartzberg Scott H. Williamson Carlos D. Bustamante Rasmus Nielsen Andrew G. Clark Eric D. Green

A remarkable characteristic of the human major histocompatibility complex (MHC) is its extreme genetic diversity, which is maintained by balancing selection. In fact, the MHC complex remains one of the best-known examples of natural selection in humans, with well-established genetic signatures and biological mechanisms for the action of selection. Here, we present genetic and functional evidenc...

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