Human lymphocytes from normal peripheral blood, thymus, spleen, thoracic duct, and peripheral lymphocytes from patients with chronic lymphatic leukemia were studied for complement receptor sites (CRL), surface immunoglobulin (SIg), and for the ability to form rosettes with sheep erythrocytes (TRFC). The two B cell markers (CRL and SIg) were found to be in overlapping, but not totally identical ...

s. The lead speaker either presents the current concepts of the topic or presents cutting-edge research within the area. Animal Models for Biomaterial and Medical Device Testing Contributing SIG: Cardiovascular SIG Invited Speakers: Allison Hayward and

We determined the prevalence and significance of finding B cells without surface immunoglobulin (SIg) light chain expression. The flow cytometry database at Johns Hopkins Medical Institutions was searched for cases in which immunoglobulin light chain staining was performed to rule out a B-cell malignant neoplasm between January 1994 and February 2000. We excluded plasma cell dyscrasias, precurs...

The ISMB Special Interest Group on Linking Literature, Information and Knowledge for Biology (BioLINK) organized a one-day workshop at ISMB/ECCB 2013 in Berlin, Germany. The theme of the workshop was “Roles for text mining in biomedical knowledge discovery and translational medicine”. This summary reviews the outcomes of the workshop. Meeting themes included concept annotation methods and appli...

Last year, SpLC an ISCA Special Interest Group (SIG) centered around Speaker and Language Characterization was born. The aims of this paper are to present the SpLC SIG, its objectives, and the work done during the first year.

The purpose of the present study was to investigate the protective effect of the σ-1 receptor (Sig-1R) agonist (+)‑pentazocin (PTZ) on pressure-induced apoptosis and death of human trabecular meshwork cells (hTMCs). The expression levels of Sig‑1R and insulin receptor (InsR) were examined in hTMCs. Cells were cultured under a pressure of 0, 20, 40, 60 and 80 mmHg for 48 h, and under 80 mmHg for...

No desenvolvimento de Sistemas de Informação Geográfica (SIG), ferramentas como servidores de mapas são utilizadas para dar suporte à busca, recuperação e visualização de mapas. Uma ferramenta de código-aberto muito utilizada é o MapServer, um ambiente de desenvolvimento de SIG para Web desenvolvido pela Universidade de Minnesota [Carvalho, 2004]. Para utilizar o MapServer é necessário que o de...

Knowledge acquisition is a bottleneck in AI applications. Neural learning is a new perspective in knowledge acquisition. In our approach we have extended Kohonen's self-organizing feature maps (SOFM) by the U-matrix method for the discovery of structures resp. classes. We have developed a machine learning algorithm, called SIG*, which automated extracts rules out of SOFM which are trained to cl...