The causes of prostate cancer are not well understood, but certain risk factors have been identified, namely age, ethnic group, family history, hormone levels and environmental inf luences. The role of androgens in the pathogenesis of prostate cancer remains unclear, but is thought to be pivotal. While androgenic stimulation is needed for prostate development and growth, serum testosterone leve...

Purpose We investigated factors affecting testosterone recovery after androgen deprivation therapy (ADT) withdrawal in patients with prostate cancer. Materials and Methods The medical records of patients who underwent radical prostatectomy with ADT were retrospectively reviewed. In all, 221 patients were included in the analysis. Testosterone recovery was defined as supra-castration (SC) (tes...

INTRODUCTION This study was designed to investigate the relationship between serum adiponectin and testosterone in patients with type 2 diabetes. MATERIALS AND METHODS Serum level of adiponectin and testosterone were prospectively measured in 65 patients with type 2 diabetes and in 20 healthy subjects. Testosterone was determined by the radio-immunoassay whereas adiponectin levels were determ...

A 74-year-old man was referred to our clinic for the work-up of digitally hard and irregularly surfaced prostate and elevated serum prostate-specific antigen (PSA). His serum PSA was elevated to 41 ng/ml, but testosterone and LH level were decreased to 23.5 ng/dl and 0.5 mIU/ml, respectively. He had a history of taking an androgenic medicine containing methyl-testosterone 2 to 3 times a week fo...

PURPOSE To compare the levels of serum cortisol and testosterone in acute and chronic central serous chorio-retinopathy (CSC). METHODS Serum cortisol and testosterone levels in 30 patients with either acute or chronic CSC were evaluated using chemiluminescent immunoassay. RESULTS The mean age was 42.43 ± 6.37 years (range, 32 to 56 years). The mean 8:00 to 9.00 a.m. serum cortisol level was...

BACKGROUND This cross-sectional study aimed to investigate the relationship between the levels of serum testosterone and the severity of chronic obstructive pulmonary disease (COPD). MATERIALS AND METHODS Using GOLD criteria, 140 male patients with COPD were categorized into mild, moderate, severe and very severe COPD groups of 35 each. Then, serum levels of testosterone, prolactin and LH of ...

conclusions it is concluded that dietary supplementation of l-carnitine has no effect on serum levels of estrogen, progesterone and testosterone in cats following ovariohysterectomy. long-term study is recommended. background the benefits of the addition of l-carnitine to the diet of cats to control weight gain after the removal of their ovaries have been highlighted recently. it is also used i...

BACKGROUND GABA can influence the steroidogenesis in peripheral and central nervoussystems. OBJECTIVES The present study investigates the interactive effect of GABAA receptors and extremely low frequency electromagnetic field on serum testosterone level of male rats. PATIENTS AND METHODS Fifty adult male rats were randomly assigned into 10 groups. Groups 2, 4, 6, 8, and 10 were exposed to E...

Background: Varicocele suggests that in addition to effects on spermatogenesis, varicocele also impairs testicular Leydig cell function with a consequential decrease in testosterone production; correction of the varicocele may result in improved serum testosterone levels. Materials and Methods: We measured preoperative serum testosterone levels in 40 infertile men with varicoceles varicocele (g...

Seminal plasma (SP) plays an important role in the motility, viability and maintenance of the fertilizing capacity of mammalian spermatozoa. This study is the first on brown bear (Ursus arctos) SP components, and has two main objectives: 1) to define the SP composition in bear ejaculate and 2) to identify variations in SP composition in relation to high and low levels of testosterone in serum d...