To evaluate renal functions in camel, the study on profiles like Serum Creatinine (SC), Serum urea nitrogen (SUN), SUN/SC ratio was undertaken in institute’s herd of camels (n=250) (Camelus dromedarius) of all age groups, both sexes and three breeds and in addition Glomerular Filtration rate (GFR) of 18 male camels of 3 breeds (n=6 each) with 6 individual replicates (Total 108 observations) wer...

Urea Nitrogen to Creatinine Ratio Related Information: Creatinine, Serum or Plasma Osmolality, Serum Urea Nitrogen, Serum or Plasma Synonyms: BUN to Creatinine Ratio Test includes: Serum creatinine and serum urea nitrogen. Background: Useful to distinguish between preand postrenal diseases, gastrointestinal bleeding, and renal diseases. High BUN/creatinine ratio: Decreased renal perfusion, hypo...

Background: Nephrotoxicity is an inherent of certain anticancer drugs. Aim: This study aimed to assess the protective effect of onion oil and selenium against cisplatin-induced nephrotoxicity in male rats. Results: Cisplatin (5 mg/kg, i.p.) caused significant increases in serum sodium, blood urea nitrogen, serum creatinine, total sodium and potassium excreted in urine, urine volume and lipid pe...

Liuwei Dihuang pill (LDP) was assessed for its effects on renal deficiency.90 STZ induced DN rats were divided into groups (n = 22) without treatment (STZ) and LDP treated (STZ-L) (n = 23), Zhenwu decoction treated (STZ-Z) (n = 22), and valsartan treated (STZ-V) (n = 23) groups, with 16 normal control rats. Total urine protein (TP), blood urea nitrogen (BUN), and serum creatinine (Cr) were meas...

BACKGROUND Diabetic nephropathy (DN) is a major cause of chronic kidney failure and characterized by excessive deposition of extracellular matrix. Evidence have shown that transforming growth factor-β1 (TGF-β1) is a key mediator in the development of DN. However, treatment of DN by blocking the TGF-β1/Smad7 pathway remains limited. Xiaokeping mixture (XKP), a traditional Chinese herbal compound...

BACKGROUND The integrase inhibitors, raltegravir and dolutegravir, are nucleoside reverse transcriptase inhibitor-sparing agents which may be used as part of first-line antiretroviral therapy for HIV. These drugs inhibit creatinine secretion through organic cation transporters, thus elevating serum creatinine without affecting glomerular filtration. We sought to determine whether subtle signs o...

Objective(s): It has been shown that adipose-derived mesenchymal stem cells (AD-MSC) have protective effects in acute kidney injury (AKI). This study was conducted to assess the therapeutic effects of AD-MSC in rats subjected to acute kidney injury by 45 min of renal ischemia followed by 48 hr of reperfusion (I/R). Materials and Methods:...

The present study was aimed to evaluate the beneficial effect of Cystone syrup in an experimental model of glycerol-induced acute renal failure (ARF) in rats. Biochemical parameters, kidney weight and histopathological evaluation were performed to conclude the beneficial effect of Cystone syrup. Administration of single dose of 50% v/v glycerol (8ml/kg.i.m) caused severe renal dysfunction assoc...

Introduction: The long time use of opium has some effects on serums biochemical factors, the determination of this variation is a new approach in understanding off addiction and relive of drug abuser health. Hence in this study, these indicators in person who were withdrawing of opium have been studied. Materials and Methods: In this cross-sectional study bloods biochemical factors such as fast...

objective(s): titanium dioxide (tio2) nanoparticles (nps) are widely used in commercial food additives and cosmetics worldwide. uptake of these nanoparticulate into humans by different routes and may exhibit potential side effects, lags behind the rapid development of nanotechnology. thus, the present study designed to evaluate the toxic effect of mixed rutile and anatase tio2 nps on serum bioc...