background: sepsis is a common clinical diagnosis. knowing the outcome of these patients is very important because it alerts the physicians. the goal of this research is to find an easy, inexpensive and accessible way for this purpose and to study the correlation between thyroid hormones and cortisol levels and the outcome of patients in sepsis. methods: in this study 55 sepsis patients were ex...

background: neonatal sepsis is a major cause of mortality and morbidity, especially in developing countries. the goal of the present study was to determine the bacterial etiology and antibiotic sensitivity patterns of neonatal sepsis.   methods: this cross sectional study was conducted on 208 neonates admitted with clinically suspected sepsis over a period of 30 months. sepsis was divided into ...

Background: Neonatal sepsis is a life-threatening disease with an incidence of 1 to 10 per 1000 live births and a mortality rate of 15% to 50%. The clinical signs are non-specific and indistinguishable from those caused by a variety of neonatal noninfectious disorders. Objective: The aim of this study was to determine the importance of CD64 expression (FcgRI), a neutrophil surface marker, in ea...

Introduction: Infections are one of the main causes of death during childhood. Epidemiologic studies in Iran showed that the incidence of neonatal sepsis was 1.8% in 1995. Moreover, the incidence of neonatal meningitis is 0.2 to 0.4 in per 1,000 live births. The aim of this study was to determine the necessity of lumbar puncture (LP) in early neonatal sepsis. Methods: In a retrospective study, ...

conclusions in the present study, we identified a key gene rps16 and a significant module involved in ribosome biogenesis in eukaryotes that were related to neonatal sepsis, which might be potential biomarkers for early detection and therapy for neonatal sepsis. background the exact interacting factor that response to the infection for neonatal sepsis is still needed to urgently to be disclosed...

Abstract Sepsis is defined as a life-threatening organ dysfunction, which caused by dysregulated host response to infection. The composition of the intestinal microbiota significantly different between patients with sepsis and healthy individuals. Intestinal microbial imbalance plays an important role in occurrence development sepsis. Our review mainly introduces mechanism involvement sepsis, e...

Background Late onset sepsis is a frequent complication of prematurity, associated with increased mortality and morbidity. Probiotics may prevent late onset sepsis in premature infants. The aim of this study was to determine prophylactic effect of oral probiotics in prevention of late onset sepsis of very preterm infants. Materials and Methods This study was a randomized, double blinded, placeb...