نتایج جستجو برای: sensitive hydrogel

تعداد نتایج: 294384  

Journal: :Journal of Polymer Science Part A: Polymer Chemistry 1992

2006
Tao Wang Sundaram Gunasekaran

The bound water fraction (XBW) of a newlydeveloped pH-sensitive, biodegradable chitosan-polyvinyl alcohol (PVA) hydrogel crosslinked with glutaraldehyde (GA) was investigated as a function of the chitosan/PVA molar ratio, GA concentration (CGA), and ionization state. Differential scanning calorimetry (DSC) was used to determine the XBW of the initial hydrogel, and of the hydrogel equilibrated i...

2015
Kelly R. Stevens Jordan S. Miller Brandon L. Blakely Christopher S. Chen Sangeeta N. Bhatia

Engineered tissue constructs have the potential to augment or replace whole organ transplantation for the treatment of liver failure. Poly(ethylene glycol) (PEG)-based systems are particularly promising for the construction of engineered liver tissue due to their biocompatibility and amenability to modular addition of bioactive factors. To date, primary hepatocytes have been successfully encaps...

Journal: :Biomaterials Science 2021

Biocasting of a bi-layered model the external elastic lamina and tunica adventitia vascular wall from fibroblast cellularized collagen click crosslinkable, cell-adhesive protease-sensitive elastin-like recombinamer hydrogel.

2018
He-Lin Xu Fu-Rong Tian Jian Xiao Pian-Pian Chen Jie Xu Zi-Liang Fan Jing-Jing Yang Cui-Tao Lu Ying-Zheng Zhao

Introduction The short lifetime of protein-based therapies has largely limited their therapeutic efficacy in injured nervous post-spinal cord injury (post-SCI). Methods In this study, an affinity-based hydrogel delivery system provided sustained-release of proteins, thereby extending the efficacy of such therapies. The affinity-based hydrogel was constructed using a novel polymer, heparin-pol...

2017
Kahye Song Shyr-Shea Chang Marcus Roper Hyejeong Kim Sang Joon Lee

Stimuli-sensitive hydrogels have been intensively studied because of their potential applications in drug delivery, cell culture, and actuator design. Although hydrogels with directed unidirectional response, i.e. capable of bending actuated by different chemical components reaction in response to several stimuli including water and electric fields, these hydrogels are capable of being actuated...

2015
Shixuan Chen Junbin Shi Min Zhang Yinghua Chen Xueer Wang Lei Zhang Zhihui Tian Yuan Yan Qinglin Li Wen Zhong Malcolm Xing Lu Zhang Lin Zhang

The purpose of this study was to permit bone marrow mesenchymal stem cells (BMSCs) to reach their full potential in the treatment of chronic wounds. A biocompatible multifunctional crosslinker based temperature sensitive hydrogel was developed to deliver BMSCs, which improve the chronic inflammation microenvironments of wounds. A detailed in vitro investigation found that the hydrogel is suitab...

2003
Richard A. Gemeinhart Chunqiang Guo

Introduction............................................................................................................245 Polymer Swelling ..................................................................................................247 Ideas for Rapid Swelling.......................................................................................248 Superporous Hydrogels ....................

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