Objective: Human semen is the jelly-like substance mainly containing semenogelin 1 (Sg1) and fibronectin (Fn) with the characteristics of coagulation and liquefaction in a short time. In our previous study, we have identified that Eppin could interact with Sg. Eppin C-terminal fragment bind the Sg fragment containing the only cysteine in human Sg I (Cys-239). Besides that, during semen liquefac...

It has been hypothesized that exposure to heavy metals may impair male reproduction. To measure the effect produced by low doses of heavy metals on semen parameters, it is necessary to clarify in which body fluids those measurements must be performed. Sixty-one men attending infertility clinics participated in our study. Concentrations of lead, cadmium, and mercury were measured in whole blood,...

The semen used in these studies was collected from healthy dairy bulls by means of an artificial vagina and was kept in a refrigerator until used. All experiments were begun within 2 hours after the semen was collected. Observations were made on the effect of inhibitors on bull sperm in the egg yolk-buffer pabulum previously described (2, 3). Semen and yolk-buffer at pH 6.8 were mixed at the ra...

Patients with human immunodeficiency virus type 1 (HIV-1) who receive antiretroviral therapy (ART) often achieve increased survival and improved quality of life. In this respect, monotherapy with darunavir/ritonavir (mDRV/r) can be a useful treatment strategy. This prospective study analyses the effect of mDRV/r on sperm quality and viral load in a group of 28 patients who had previously been g...

Background: Declines in semen quality over time are not well understood. It is suspected that infectious disease may affect reproductive function. The aim of this study was to investigate semen quality in men in infertile relationships who were under investigation for couple infertility and attended a clinic for routine semen analysis over a period of 15years. Materials and Methods: We investig...

Semen from 10 932 male partners of infertile couples was analysed and sperm parameter trends were evaluated at the Reproduction Biology Laboratory of the University Hospital of Marseille (France) between 1988 and 2007. After 3-6 days of abstinence, semen samples were collected. Measurements of seminal fluid volume, pH, sperm concentration, total sperm count, motility and detailed morphology of ...

The Mullerian glands of adult male caecilians, which are derived from the undifferentiated Mullerian ducts, secrete many constituents similar to those found in the semen of birds and mammals. These include fructose, acid phosphatase, and mucopolysaccharides. The pH of the secretion is similar to that of semen. Caecilians reproduce terrestrially using intromission and internal fertilization. It ...

BACKGROUND A number of laboratory tests have been developed to determine properties of spermatozoa quality but few have been adopted into routine clinical use in place of the WHO semen analysis. We investigated whether Atp6v0a2 (a2 isoform of vacuolar ATPase) is associated with abnormal semen quality and changes in chemokine-cytokine profiles in infertile men. PATIENTS AND METHODS Semen sampl...

HIV and AIDS infection are major public health problems in sub-Saharan Africa. is spread through contact with certain body fluids from a person HIV, such include; blood, semen, pre-seminal fluid, vaginal fluids, rectal breast milk. attacks destroys the CD4 cells