CONTEXT The terms "palliative sedation" and "terminal sedation" have been used to refer to both proportionate palliative sedation, in which unconsciousness is a foreseen but unintended side effect, and palliative sedation to unconsciousness, in which physicians aim to make their patients unconscious until death. It has not been clear to what extent palliative sedation to unconsciousness is acce...

OBJECTIVE As the number of diagnostic imaging studies performed has increased, the demand for sedation in support of these radiologic tests has also increased. Our objectives were to (1) assess the safety and efficacy of a radiology sedation service that is staffed exclusively by pediatric emergency medicine (PEM) physicians, (2) determine the frequency and the type of commonly performed pediat...

OBJECTIVE The updated clinical practice guidelines for the management of pain, agitation, and delirium recommend either daily sedation interruption or maintaining light levels of sedation as methods to improve outcomes for patients who are sedated in the ICU. We review the evidence supporting both methods and discuss whether one method is preferable or if they should be used concurrently. DAT...

Flexible bronchoscopy is commonly performed by respiratory physicians and is the gold standard for directly visualising the airways, allowing for numerous diagnostic and therapeutic interventions. With the widespread use of flexible bronchoscopy and the evolution of interventional bronchoscopy with more complex and longer procedures, physicians are placing increasing importance on the use of se...

Objective- This study aimed to compare sedation efficacy in intranasal administration of xylazine, diazepam and midazolam with or without ketamine in Chough. Design- To determine the sedation efficacy, an experimental in vivo study was employed. Animals- Seven healthy Choughs were examined in the current study. Procedu...

The 2018 Critical Care Medicine Guidelines for Analgesia and Sedation in the ICU Good Practice Statement emphasized importance treatment of pain taking precedence over sedation. Within these guidelines, a multimodal analgesia approach is standard care ICU, which often includes initiation opioids. 1 As practice has shifted to prioritize management sedation, opioids have been administered frequen...

Most fearful and uncooperative children can be managed with behavioral management techniques. However, when behavioral management strategies fail, some form of pharmacologic sedation or anesthesia has to be utilized. Midazolam, one of the commonly used oral sedation agent in children has several characteristics such as safety of use, rapid onset and some degree of amnesia that makes it a desira...

BACKGROUND The aim of this study was to evaluate the use of inhaled methoxyflurane (Penthrox) in the reduction of dental anxiety in patients undergoing mandibular third molar removal in a specialist surgical suite and compare it to the conventional nitrous oxide sedation. METHODS A prospective randomized, non-blinded crossover design study of 20 patients receiving two types of sedation for th...

1 regarding the safety of sedation practice done by untrained sedation practitioners. Non-anaesthesiologists are involved in sedation worldwide, and I agree that sedation of patients for minor procedures 'is here to stay'. But I am concerned that a dark picture is painted of conscious sedation, which is very safe when done by trained practitioners. In order to help solve the problem, we need to...

BACKGROUND The low shock energy used during internal atrial defibrillation may decrease the need for sedation during defibrillation with an implantable atrial defibrillator. METHODS AND RESULTS The atrial defibrillator (Metrix Atrioverter) was implanted in 12 patients. During the in-hospital treatment of atrial fibrillation (AF) episodes, intravenous sedation was given only on patient request...