In this article we briefly review theories about the ecological roles of microbial secondary metabolites and discuss the prevalence of multiple secondary metabolite production by strains of Streptomyces, highlighting results from analysis of the recently sequenced Streptomyces coelicolor and Streptomyces avermitilis genomes. We address this question: Why is multiple secondary metabolite product...

Background: Tissue culture is a new approach for production of secondary metabolites with many advantages over conventional methods. Elicitors such as nano particles are molecules that can stimulate the production of secondary metabolites. Objective: This study was conducted to evaluate the effects of some nano particles on mucilage production in Linum usitatissimum under tissue culture condit...

Background: Biotechnologic methods are common for secondary metabolites production from the plants and other sources in pharmaceutical sciences. Hairy root cell lines as the biotechnologic method have been used for in vitro production of major plant metabolites. Objective: In this study, hairy roots of Hypericum Perforatum have been prepared using the seeds and bio transformed by bacteria. Fin...

a case of an acute intestinal obstruction in a 64 -year - old man, due to cicatriceal stricture of tlie left colon with secondary enteroliths in colon, is presented. enteroliths in colon arc rare and it is suggested that stasis is the most important factor in their production as ihey arc. most commonly associated with an intestinal sricturc.

Fungi and plants are rich sources of thousands of secondary metabolites. The genetically coded possibilities for secondary metabolite production, the stimuli of the production, and the special phytotoxins basically determine the microscopic fungi-host plant interactions and the pathogenic lifestyle of fungi. The review introduces plant secondary metabolites usually with antifungal effect as wel...

Zinc and iron nano-oxides (100 ppb) were promoted the hypericin and hyperforin production in Hypericum perforatum cell suspension culture. High performance liquid chromatography method was used for detectection and identification of hypericin and hyperforin in H. perfuratum cell suspension cultures elicited with different concentrations of zinc and iron nano-oxide (0, 50, 100 and 150 ppb) after...

Plants are important source for the discovery of new products of medicinal value for drug development and plants secondary metabolites are unique sources for pharmaceuticals food additives, flavors and others industrial values. Commercial importance of these secondary metabolites has resulted in a great interest in its production and in exploring possibilities of enhancing its production by mea...

Hairy root culture is an effective method to produce secondary metabolites. In fact, hairy roots are genetically and biologically stable and also they are able to produce metabolites without hormones. Chicory (Cichorium intybus L.) is one of the most important medicinal plants with valuable medicinal compounds. In this research, hairy roots were induced by different Agrobacterium rhizogenes str...