BACKGROUND Rheumatic heart disease (RHD) remains a major health concern for Aboriginal Australians. A key component of RHD control is prevention of recurrent acute rheumatic fever (ARF) using long-term secondary prophylaxis with intramuscular benzathine penicillin (BPG). This is the most important and cost-effective step in RHD control. However, there are significant challenges to effective imp...

BACKGROUND Cellulitis (erysipelas) is a recurring and debilitating bacterial infection of the skin and underlying tissue. We assessed the cost-effectiveness of prophylactic antibiotic treatment to prevent the recurrence of cellulitis using low dose penicillin V in patients following a first episode (6 months prophylaxis) and more recurrent cellulitis (12 months prophylaxis, or 6 months in those...

Abstract Background Erythema marginatum is an uncommon presentation in children with acute rheumatic fever and it one of the major criteria needed to make a diagnosis. It seen less than 10% cases. also reported be difficult detect black-skinned children. This first only patient present above since inception unit about 14 years ago Nigeria as far authors are aware, after careful literature searc...

A 3-year-old boy was admitted to the emergency department with right lower limb pain, edema, and livedoid discoloration that occurred immediately after intramuscular injection of benzathine penicillin. The patient was diagnosed with Nicolau syndrome, a rare complication of intramuscular injection presumed to be related to the inadvertent intravascular injection. It was first reported following ...

AIM Respiratory tract infections are considered the major problem of equine worldwide. Strangles is an infectious and highly contagious respiratory bacterial disease of equine caused by Streptococcus equi. This study is aimed to evaluate some clinical and epidemiological investigation associated with strangles and to study the hematological and biochemical changes in 20 Arabian horse naturally ...

Doxycycline is the preferred recommended second-line treatment for the treatment of early syphilis. Recent reports showed a declining efficacy trend of doxycycline in treatment of early syphilis. The aim of our study was to assess the serological response to the treatment for early syphilis with doxycycline compared with benzathine penicillin G and evaluate whether doxycycline is still an effec...

A 35-year-old man presented with a 3-week history of asymptomatic ulcerated lesions in the tongue (Fig. 1). He developed erythematous papules in the trunk and legs at the same time. The patient had no other systemic symptoms and reported having had unprotected sexual intercourse. Testing for the human immunodeficiency virus was positive. VDRL testing was positive with a titer of at least 1:64. ...