Nuzhat A. Ahmad, Philadelphia, PA Joseph Anderson, White River Junction, VT Darren M. Brenner, Chicago, IL Andrew T. Chan, Boston, MA Francis K. L. Chan, Hong Kong, China Lin Chang, Los Angeles, CA Tsutomu Chiba, Kyoto, Japan Massimo Colombo, Milan, Italy B. Joseph Elmunzer, Ann Arbor, MI Timothy B. Gardner, Lebanon, NH Lauren B. Gerson, Stanford, CA W. Ray Kim, Rochester, MN Paul Y. Kwo, India...

Recent research has helped software developers to obtain better insights into workflow technology, understand its interdisciplinary nature, and realize its potential for building flow-independent applications. As Petrie and Sarin point out, workflow is no longer just “some sort of planned document routing” [14]. Therefore, an increasing number of developers are embracing workflow technology [20...

The authors analyzed over 200 cases of acute poisoning with sarin, soman and VX chemical, determined risk of the poisoning in various conditions. The clinical manifestations of acute poisoning and the long-term effects are presented.

Vol. XLIX (August 2012), 564–580 *Shikhar Sarin is Kirk and Marsha Smith Professor of Marketing, College of Business and Economics, Boise State University (e-mail: ssarin@ boisestate. edu). Goutam Challagalla is Associate Professor of Marketing (e-mail: goutam. [email protected]), and Ajay K. Kohli is Gary T. and Elizabeth R. Jones Chair (e-mail: [email protected]), College of ...

Organophosphorus (OP) compounds are organic derivatives of phosphorus that have largely been used as pesticides and nerve agents. Tetraethylpyrophosphate was synthesized in 1854 as the first OP cholinesterase inhibitor. During 1934–1944, Gerhard Schrader, a German chemist at I. G. Farben industries and his coworkers synthesized about 2,000 OP compounds, including parathion as a pesticide and ta...

The nerve agents soman, sarin, VX, and tabun are deadly organophosphorus (OP) compounds chemically related to OP insecticides. Most of their acute toxicity results from the irreversible inhibition of acetylcholinesterase (AChE), the enzyme that inactivates the neurotransmitter acetylcholine. The limitations of available therapies against OP poisoning are well recognized, and more effective anti...

During the last five decades, five pyridinium oximes were found to be worthy of use as antidotes against nerve agents in humans: pralidoxime, in a form of chloride or PAM-2 Cl and mesylate or P2S (against sarin, cyclosarin and VX), trimedoxime or TMB-4 and obidoxime or LüH-6 (both against tabun, sarin and VX), HI-6 (against sarin, soman, cyclosarin and VX) and HLö-7 (against all the five nerve ...

I The effects of some muscarinic antagonists, namely, N-ethyl-2-pyrrolidylmethyl-cyclopentylphenyl glycollate (PMCG), N-methyl-4-piperidyl-phenylcyclohexyl glycollate (PPCG, racemate and R and S enantiomers) and 4'-N-methyl-piperidyl-1-phenyl-cyclopentane carboxylate (G3063) on organophosphate (sarin, soman)and carbamate (neostigmine)-induced twitch augmentation have been studied in cat soleus ...

The applicability of HKUST-1 for the degradation of sulfur mustard and sarin simulants was studied with and without coadsorbed water. Degradation was found to be via hydrolysis and dependent on the nucleophilic substitution reaction, vapour pressure and molecular diameter of the toxicants.