May/June 2001, Vol.8, No.3 Cancer Control 215 Sarcomas are malignant neoplasms arising in nonepithelial tissues of the body. The early manifestations of these somewhat rare tumors are commonly overlooked and the diagnosis is often delayed because they are not commonly encountered in practice. Fewer than 8,000 soft-tissue sarcomas and even fewer bone sarcomas are diagnosed annually in the United...

Morcellation allows the removal of a large uterus and fibroids through small incisions with minimally invasive surgery. It helps to prevent complications associated in both hysterectomy myomectomy operations. Currently, there is much debate regarding use power morcellation laparoscopic myomectomy, mainly due risk peritoneal dissemination undiagnosed uterine sarcomas. Unfortunately, no valid pre...

Sarcomas are a heterogeneous group of neoplasms of mesenchymal origin. Approximately 80% arise from soft tissue and 20% originate from bone. To date more than 100 sarcoma subtypes have been identified and they vary in molecular characteristics, pathology, clinical presentation and response to treatment. While sarcomas represent <1% of adult cancers, they account for approximately 21% of paediat...

INTRODUCTION Primary chest wall sarcomas are rare mesenchymal tumors and their mainstay of therapy is wide surgical resection. We report our single-institution, multidisciplinary experience with full-thickness resection for primary chest wall sarcomas. METHODS A retrospective review of our prospectively maintained databases revealed that 51 patients were referred for primary chest wall sarcom...

A variety of bone and soft-tissue sarcoma cell lines have been shown to express receptors for insulin-like growth factor-1 (IGF-1) and to respond mitogenically to IGF-1 in vitro. We have recently demonstrated evidence of IGF dependency in murine MGH-OGS and RIF-1 sarcomas, which express relatively high and intermediate levels of IGF-1 receptors. Overexpression of IGF-1 receptors and/or IGF liga...

PATIENT Female, 60 FINAL DIAGNOSIS: Rhabdomyosarcoma of the breast Symptoms: Lump in axilla Medication: - Clinical Procedure: Mastectomy Specialty: Oncology. OBJECTIVE Rare disease. BACKGROUND Primary nonepithelial malignancies of the breast include primary breast sarcomas, therapy-related breast sarcomas, the phyllodes tumors, and primary breast lymphomas. They account for less than 5% of ...

Introduction. Primary breast sarcomas (PBSs) are rare nonepithelial breast tumors compromised of mesenchymal mammary tissue. Although its rare nature has made the best mode of PBS treatment difficult to determine, it seems better to treat it more like a sarcoma creating clear negative margins verses breast carcinoma utilizing lumpectomy, partial mastectomy, and total mastectomy. Case. A 47-year...

Sarcomas are a heterogeneous group of tumors that are traditionally classified according to the morphology and type of tissue that they resemble, such as rhabdomyosarcoma, which resembles skeletal muscle. However, the cell of origin is unclear in numerous sarcomas. Molecular genetics analyses have not only assisted in understanding the molecular mechanism in sarcoma pathogenesis but also demons...

Abstract Aims The rarity of thoracic sarcomas leads to challenges in their diagnosis and evidence-based management. We aim investigate the management outcomes primary sarcoma patients under care our tertiary centre Sarcoma Service over a three-year period. Methods Data all discussed at multidisciplinary meetings from 2017–2019 were collected local electronic database. Results 65 met inclusion c...

Soft tissue sarcomas are rare tumours with infrequent identified aetiological factors. Several genetic syndromes as well as previous radiation therapy and/or chronic lymphoedema have been suspected to predispose to some soft tissue sarcomas. Between January 1997 and September 2005, we carried out a prospective descriptive study to estimate the frequency of some particular etiological factors am...