The saponification of an aromatic ester with an aqueous sodium hydroxide was studied within a heterogeneous reaction medium in order to determine the overall kinetics of the selected system. The extended thermo-kinetic model was developed compared to the previously used simple one. The reaction rate within a heterogeneous liquid-liquid system incorporates a chemical kinetics term as well as mas...

The reaction of N,N’-persubstituted selenoacrylamides with alkyl bromoacetates gives rise to the formation of alkyl derivatives of N,N-disubstituted 2-aminoselenophene-5-carboxylates which can be transformed by saponification into corresponding 5-carboxylic acids. These compounds decompose by heating under formation of hitherto unknown N,N-disubstituted 2-amino-5H-selenophenes their spectral an...

Regioselective N-alkylation of 4-chloro-2-methoxy-7H-pyrrolo[2,3d]pyrimidine (6) with ethyl 3-bromopropionate under liquid-liquid phase-transfer reaction conditions gave the ester 7a. Its saponification yielded the acid 7b. The logP values of a series of N(9)-functionalized purines and purine isosteres were calculated.

Malaksadi taila was prepared as per Ayurvedic formulary and was analysed. The specific gravity, saponification number, iodine number and acid number were 0.915, 199, 102 and 2 respectively. The drug resolved into two spots in the solvent n-butanol, acetic acid, water (75:15:10). The visible spectrum showed two peaks at 420-30 nm and 660 nm.