Regioselective N-alkylation of 4-chloro-2-methoxy-7H-pyrrolo[2,3d]pyrimidine (6) with ethyl 3-bromopropionate under liquid-liquid phase-transfer reaction conditions gave the ester 7a. Its saponification yielded the acid 7b. The logP values of a series of N(9)-functionalized purines and purine isosteres were calculated.

Malaksadi taila was prepared as per Ayurvedic formulary and was analysed. The specific gravity, saponification number, iodine number and acid number were 0.915, 199, 102 and 2 respectively. The drug resolved into two spots in the solvent n-butanol, acetic acid, water (75:15:10). The visible spectrum showed two peaks at 420-30 nm and 660 nm.

A method is described for accurate and reproducible measurement of squalene in plasma, feces, urine, bile, and tissue that depends on isolation by alumina column chromatography after mild saponification and on measurement by gas-liquid chromatography. Recoveries from all tissues exceeded 80% and from plasma 96%; losses were accurately corrected by appropriate additions of squalene as an overall...

The title compound, C(10)H(14)N(2)O(3)·H(2)O, was synthesized by alkyl-ation of methyl 3-(1H-pyrrole-2-carboxamido)-propion-ate with ethyl bromide, followed by saponification and acidification. In the crystal structure, inter-molecular O-H⋯O and N-H⋯O hydrogen bonds link the mol-ecules, forming layers parallel to the ac plane.

This study was conducted to assess three extraction methods for the determination of fatty acid compositions and carotenoids (lutein, zeaxanthin, β-carotene, and α-carotene) from marine microalgae, Nannochloropsis oculata (NO) and Chaetoceros gracilis (CG). For this purpose, three different extraction methods for the determination of fatty acids (dichloromethane:methanol, water:propan-2-ol:hexa...

Soap is a product from the hydrolysis of fats into fatty acids and glycerol under alkaline conditions, known as saponification process. Many factors affect process to produce liquid soap with proper quality, including viscosity density values. Saponification time stirring speed are that quality be observed. Using strong bases electrolysis machines well coconut oil natural comperland innovations...