Salivary gland cancers are uncommon malignancies of the head and neck region. Their site of origin can be major (parotid, submandibular and sublingual) or minor salivary gland (palate, nasal cavity, paranasal sinuses, trachea and lacrimal gland). Of all the salivary gland neoplasms, 85% are benign and 15% are malignant. Salivary gland malignancies comprise 3-6% of all head and neck cancers (Pin...

Warthin’s tumor is the most common monomorphic adenoma of parotid gland. It can be coexistent with other salivary gland tumors or metachronous, multifocal, unilateral, bilateral which perplexes diagnosis hence delaying over/under treating ailment. Rare cases are described in young population especially non-smoker females. We present a case arising left 20-year-old female.

Obtaining reliable pre-operative diagnosis is crucial in planning treatment for patients with salivary gland tumors. The purpose of this study was to evaluate the accuracy of pre-operative clinical diagnosis of salivary gland tumors managed at a single tertiary university hospital over a period of 20 years. A retrospective analysis of the period between 1992 and 2011 was carried out to review t...

The etiology of Warthin's tumor, a benign parotid gland tumor, is unknown. Recent evidence suggests a possible relation with cigarette smoking as well as increasing incidence. We reviewed the medical record of subjects with a major salivary gland tumor newly diagnosed in Jefferson County, Alabama, from 1968 to 1989, and identified 149 Warthin's tumors. The 533 cases with other major salivary gl...

OBJECTIVES The present study was undertaken to assess and compare the immunohistochemical expression of Bcl-2 in selected benign and malignant salivary gland tumors. STUDY DESIGN A total of 50 cases of buffered formalin-fixed, paraffin embedded tissues of previously diagnosed cases of benign and malignant salivary gland tumors from the archives of Department of Oral and Maxillofacial Patholog...

Salivary gland neoplasms are a heterogeneous and important group of tumors of the Oral and Maxillofacial Pathology. They comprise from 2 to 3% of all the salivary gland lesions and tumors1,2 because their heterogeneity, since several years, different classifications based in clinical or microscopic criteria had been appeared.3-7 The most recent and most widely used is that proposed by Seifert e...

Pleomorphic adenoma is a benign salivary gland tumor that represents less than 5% of benign tumors in childhood. World literature suggests salivary gland tumors account for less than 3% of the head and neck tumors and benign Pleomorphic adenoma of minor salivary glands arising de novo is very rare. Here we report a case of Pleomorphic adenoma of minor salivary glands occurring on the palate of ...

ABSTRACT Introduction: Pleomorphic adenoma is the most common tumor of the salivary gland. The tumor most commonly arises in the parotid or submandibular salivary glands. Infrequently, it arises from minor salivary glands. Minor salivary gland tumors are mostly malignant. Case Report: We report four cases of pleomorphic adenoma of hard palate. All four cases range from 30–45 years. All were ben...

Over the past few decades, salivary gland tumor pathology has evolved. This includes recognition of newly defined entities as well as reclassification of other salivary gland tumors [1]. The development of genetic tests have shown that some salivary gland tumors have genetic abnormalities which are specific to a histologic type such as MECT1– MAML2 gene fusion in mucoepidermoid carcinoma and PL...

BACKGROUND Salivary gland tumors are among malignancies that have high recurrence rate. Immune responses in salivary gland tumors have not been well elucidated. T helper type 1 (Th1) and Th2 cytokines have been reported to play a role in the outcome of head and neck cancers. OBJECTIVE To evaluate the serum levels of interferon gamma (IFN-γ), as the hallmark of Th1 cytokines, and interleukin-4...