BACKGROUND Sand fly saliva helps parasite establishment and induce immune responses in vertebrate hosts. In the current study, we investigated the modulation of Phlebotomus papatasi salivary gland antigen expression by seasonal and biological factors. METHODS Sand flies were grouped according to physiological stages such as unfed, fed, semi-gravid, gravid, parous, nulliparous, infected or non...

OBJECTIVE This study proposes a revision of the literature on the current techniques employed in salivary gland biopsy. METHODS A systematic review of the literature between January 1990 and January 2010 was conducted using MEDLINE, Embase and the Cochrane Central Register of Controlled Trials. The search terms were: 'biopsy AND parotid AND Sjögren'; 'biopsy AND sublingual salivary gland AND ...

Epithelial myoepithelial carcinoma is a rare biphasic low grade neoplasm of salivary glands; it most commonly occurs in the parotid gland but can also arise in minor salivary glands. Here a case of 58-year-old female presented with left cheek swelling of one-year duration. CT scan revealed a localized submandibular salivary gland tumor mass not involving surrounding tissues. Histological examin...

Hemangiomas are defined as soft tissue lesions in the maxillofacial or oral region. Hemangiomas of salivary glands constitute 30% of the non-epithelial tumors in major salivary glands.  Benign tumors in salivary glands are located 85% in parotid gland and 13% in submandibular gland. We present a case of submandibular hemangioma in an infant patient that had some complications and a challenging ...

A neoplastic salivary cell line with an ultrastructure similar to that of an intercalated duct cell of the salivary gland, established from a human submandibular salivary gland, has been used in our laboratory as a model for studying mechanisms regulating cytodifferentiation in salivary glands. The expression of neurofilaments (Mr 200,000, 160,000, and 68,000) in the neoplastic human salivary i...

Despite a pivotal role in salivary gland development, homeostasis, and disease, the role of salivary gland mesenchyme is not well understood. In this study, we used the Col1a1-GFP mouse model to characterize the salivary gland mesenchyme in vitro and in vivo. The Col1a1-GFP transgene was exclusively expressed in the salivary gland mesenchyme. Ex vivo culture of mixed salivary gland cells in DME...

Centrally occurring salivary gland tumors are rare. Because of a considerable overlap between the clinical and histopathological features, this group of tumors often produces a diagnostic difficulty to the clinicians and oral pathologists. Acinic cell carcinoma (ACC) is an unusual, low-grade, malignant salivary gland tumor that represents approximately 2% of the salivary gland tumors with almos...

by increasing number of vessels. Salivary gland tumors are uncommon and their overall incidence is about 3 per 100000 per year. Salivary gland hemangioma makes up 1 % of all salivary gland tumors. Trismus resulting from parotid hemangioma is so rare. The patient was a 6-month-old boy with a huge lesion in his right parotid who referred to Shahid sadoughi hospital of Yazd, Iran. The lesion appea...

Introduction: Submandibular gland excision is the gold standard treatment for submandibular gland disease. Although submandibulectomy is a relatively standardized surgical procedure, complications are frequently reported. These complications include nerve paralysis or paresis, aesthetic sequelae, hematoma, salivary fistulas or sialoceles, wound infections, hypertrophic scars and inflammations c...

Chronic sclerosing sialadenitis or Küttner tumor is an unusual chronic inflammatory disease of the salivary gland that mimics a malignant neoplasm clinically because of presentation as a hard mass. The diagnosis can only be made histologically and is an underrecognized entity. Recent studies have shown important features that characterizes the disease mainly as an autoimmune reaction. The aim o...